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Organosulfur Compounds in Garlic for Gastric Cancer Treatment: Anticancer Effects, Overcoming Drug Resistance, and Mechanisms.
Recent Pat Anticancer Drug Discov
January 2025
Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, P.R. China.
Garlic has been consumed globally as a functional food and traditional medicine for various ailments. Its active organosulfur compounds (OSCs) have demonstrated significant anticancer properties, particularly against gastric cancer. However, a comprehensive review of these effects and the underlying molecular mechanisms, including their role in overcoming drug resistance, is currently lacking.
View Article and Find Full Text PDFInterparental mutually responsive orientation during pregnancy impacts toddler socioemotional development by promoting parent-infant relational dynamics.
Dev Psychopathol
January 2025
Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Child socioemotional difficulties emerge as early as infancy, increase over time, and place children at risk for future internalizing and externalizing symptoms. The aim of the present study was to investigate pathways that originate within the interparental relationship during pregnancy and unfold during infancy that mitigate risk for toddler socioemotional difficulties and to examine the differential effects of these pathways for children with varying degrees of temperamental fearfulness. Specifically, we examined whether dyadic (MRO; i.
View Article and Find Full Text PDFNurses' Recognition and Care of Thirst in Perioperative Patients in Japan.
Cureus
December 2024
Department of Biological Science and Nursing, Yokohama City University Graduate School of Medicine, Yokohama, JPN.
Purpose: Postoperative thirst is common and distressing to patients, as is pain and nausea. The causes of postoperative thirst are complex and include factors like preoperative fasting, perioperative fluid loss, and certain anesthesia medications. Effective care for postoperative thirst has been shown in post-anesthesia care units (PACUs), but many Japanese hospitals lack PACUs or do not address thirst in their PACUs.
View Article and Find Full Text PDFOccupational Performance in the Discipline of Occupational Therapy During COVID-19 at a Public University in KwaZulu-Natal.
Occup Ther Int
January 2025
Discipline of Occupational Therapy, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
The application of the person-environment-occupation-performance (PEOP) model in occupational therapy education offers valuable insights into the interaction between person, environment, and occupational factors and how these elements influenced the strategies used to adapt and navigate the transformation of health professions education during the COVID-19 pandemic. This study explored how individual characteristics, contextual demands, and the nature of educational occupations shaped the adaptation and performance of educators and students. The study used a qualitative, exploratory research design at a public higher education institution (HEI) in South Africa, focusing on the occupational therapy program.
View Article and Find Full Text PDFSingle-port robot-assisted pyeloplasty through supine anterior retroperitoneal access.
Indian J Urol
January 2025
Norris Comprehensive Cancer Center, Institute of Urology, University of Southern California, Los Angeles, CA, USA.
This video explores the technique of robot-assisted pyeloplasty using the Da-Vinci Single-Port robot through the supine anterior retroperitoneal access in a 28-year-old male with a right-sided ureteropelvic junction obstruction. The patient was placed in a supine position, with a 10°-20° elevation of the ipsilateral flank. Retroperitoneal access was obtained at the McBurney's point for the placement of the port.
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