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Periorificial dermatitis in infants and preschoolers - a narrative review.
Eur J Pediatr
January 2025
Department of Dermatology & Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.
Periorifical dermatitis (POD) is a papular, chronic inflammatory skin disease commonly seen in women in their 2nd to 4th decade of life. The major differential diagnosis is persistent acne. In children, POD is less common than in adults.
View Article and Find Full Text PDFEfficacy of 4% tetracaine gel and lidocaine-prilocaine cream in reducing local anesthetic injection pain in upper eyelid blepharoplasty: a randomized, single-blinded, controlled trial.
BMC Ophthalmol
December 2024
Department of Ophthalmology, The Second Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Background: The injection of local anesthetics, an extremely painful procedure, leads to a reduction of patients' acceptance.
Objective: To investigate the efficacy and adverse reactions of 4% tetracaine gel (TG) and lidocaine-prilocaine cream (LPC) on reducing the local anesthetic injection pain for upper eyelid blepharoplasty.
Methods: Sixty participants were equally divided into three groups.
Ocular and palpebral manifestations of mastocytosis: A prospective single-center study.
Ann Dermatol Venereol
November 2024
Departement of Dermatology, Hôpital Privé Francheville, Périgueux, France. Electronic address:
Background: Ocular discomfort has been described as a frequent symptom in patients with mastocytosis, a rare disease resulting from accumulation of mast cells in organs.
Objectives: This study aims to assess the frequency and describe the nature of ocular and palpebral abnormalities in mastocytosis patients.
Patients And Methods: We conducted a prospective, single-center study in adult mastocytosis patients, who were systematically examined by a dermatologist and an ophthalmologist with determination of tear cytokine levels.
Design and validation of a preclinical model for oral commissure and lower eyelid thermal injury.
Burns
February 2025
Department of Otolaryngology - Head and Neck Surgery, Brooke Army Medical Center, JBSA Fort Sam Houston, TX, USA; United States Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA; Department of Otolaryngology - Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Article Synopsis
- Oral commissure stenosis and lower eyelid ectropion from burns are difficult to treat due to a lack of preclinical models; this study describes a method for inducing controlled burns in swine to aid future research.
- The experiment involved inducing burns of various durations (10 to 30 seconds) on swine and observing changes over time using techniques like laser speckle imaging for assessing tissue health and healing.
- Results indicated that longer burn times led to more severe tissue damage and inflammation, but no significant functional impairments were noted, suggesting the need for further exploration of treatments with this new burn model.
Umbilical Cord Blood Platelet Lysate Eyedrops for the Treatment of Severe Ocular Surface Disorders in Graft vs. Host Disease Patients: Clinical Study.
Life (Basel)
October 2024
Division of Rheumatology, A.O.U. "Policlinico-San Marco", 95123 Catania, Italy.
Article Synopsis
- * Traditional treatments for GvHD-related eye issues often fail, prompting the exploration of umbilical cord blood platelet lysate eyedrops as a potential new therapy.
- * A study involving 22 patients with severe ocular surface disorders tested the safety and effectiveness of these eyedrops, using various evaluation methods to compare results before and after treatment.
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