The results of studies of the mitosis pathology performed for many years on the material of tumour biopsies are summarized. It is shown that the determination of the tissue mitotic regimen is a theoretically founded method of cytological analysis that gives the pathologist a possibility for a more objective morphological diagnostics of pretumourous conditions and malignant tumours. The availability of this method makes it possible to recommend its wide use in the clinical oncomorphology provided the conditions assuring the minimal alteration of dividing cells (early fixation and cutting of the material) are strictly respected.

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