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Evaluation of machine learning techniques for real-time prediction of implanted lower limb mechanics.
Front Bioeng Biotechnol
January 2025
Center for Orthopaedic Biomechanics, University of Denver, Denver, CO, United States.
Introduction: Accurate prediction of knee biomechanics during total knee replacement (TKR) surgery is crucial for optimal outcomes. This study investigates the application of machine learning (ML) techniques for real-time prediction of knee joint mechanics.
Methods: A validated finite element (FE) model of the lower limb was used to generate a dataset of knee joint kinematics, kinetics, and contact mechanics.
Development of a Deep Learning Model for Automating Implant Position in Total Hip Arthroplasty.
J Arthroplasty
January 2025
Vanderbilt University Medical Center, Department of Orthopaedic Surgery.
Introduction: Novel methods for annotating antero-posterior (AP) pelvis radiographs and fluoroscopic images with deep-learning models have recently been developed. However, their clinical use has been limited. Therefore, the purpose of this study was to develop a deep learning model that could annotate clinically relevant pelvic landmarks on both radiographic and fluoroscopic images and automate total hip arthroplasty (THA)-relevant measurements.
View Article and Find Full Text PDFImproved Outcomes and Resource Use With Normothermic Machine Perfusion in Liver Transplantation.
JAMA Surg
January 2025
Division of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix.
Importance: Normothermic machine perfusion (NMP) has been shown to reduce peritransplant complications. Despite increasing NMP use in liver transplant (LT), there is a scarcity of real-world clinical experience data.
Objective: To compare LT outcomes between donation after brain death (DBD) and donation after circulatory death (DCD) allografts preserved with NMP or static cold storage (SCS).
Epidemiology, diagnosis and treatment of anterior prostate cancer.
Nat Rev Urol
January 2025
Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Anterior prostate cancers (APCs) are a group of impalpable neoplasms located in regions anterior to the urethra, which comprise the transition zone, apical peripheral zone and anterior fibromuscular stroma. These regions are typically undersampled using conventional biopsy schemes, leading to a low detection rate for APC and a high rate of false negatives. Radical prostatectomy series suggest prevalence rates of at least 10-30%, but transperineal systematic biopsy is ideal for diagnosis, particularly where multiparametric MRI is unavailable.
View Article and Find Full Text PDFOne-Year Real-World Outcomes of Ab-Externo Gel Stent Placement From the EXPAND Study.
J Glaucoma
January 2025
Wills Eye Hospital Glaucoma Service, Philadelphia, PA, USA.
Prcis: In the real-world, retrospective, EXPAND study of consecutive adults with glaucoma, ab-externo gel stent implantation effectively lowered intraocular pressure (34%) and the medication burden (61%), with transient/self-resolving hypotony as the most frequent adverse event (28%).
Purpose: To assess effectiveness and safety of ab-externo gel stent (GS) implantation in glaucoma.
Methods: Multicenter, real-world, retrospective study.
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