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Clinical Outcomes and Complications of Total Knee Arthroplasty with Posterior-Stabilized and Cruciate-Retaining Prostheses in Osteoarthritis Patients with Valgus Deformity.
Ann Ital Chir
March 2025
Department of Orthopedic Trauma, The Affiliated Hospital of Gansu University of Traditional Chinese Medicine, 730020 Lanzhou, Gansu, China.
Aim: This study aimed to evaluate the short- and long-term outcomes and complications of total knee arthroplasty (TKA) using posterior-stabilized (PS) and cruciate-retaining (CR) prosthesis in patients with osteoarthritis (OA) and valgus knee deformity.
Methods: A retrospective analysis was conducted on 200 patients with OA and valgus knee deformity who underwent TKA between February 2021 and November 2023. The cohort was divided into the PS group (n = 108) and the CR group (n = 92).
Improving maternal postpartum access to care through telemedicine (IMPACT): A multi-center randomized controlled trial of postpartum interventions to improve access and outcomes.
Contemp Clin Trials
March 2025
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:
Background: Postpartum care is essential for maternal health and significantly impacts long-term health outcomes, yet it remains inadequately addressed, particularly among Non-Hispanic Black and Hispanic individuals. The primary objective of the Improving Maternal Postpartum Access to Care through Telemedicine (IMPACT) study is to compare the effectiveness of two postpartum care models on early postpartum complication detection, hospital readmission prevention, postpartum health knowledge, quality of life, and chronic medical condition management among medically underserved individuals.
Method: The IMPACT study is a multi-center, randomized controlled trial conducted at Parkland Hospital in Dallas, Texas, and Grady Memorial Hospital in Atlanta, Georgia.
Phenotypic advantages and improved genomic stability following selection in advanced selfing-generations of Brassica allohexaploids.
J Genet Genomics
March 2025
National Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China. Electronic address:
Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids. A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type (AABBCC) by combining different diploid and allotetraploid crop species. However, early-generation allohexaploids often face challenges like unstable meiosis and low fertility, and the phenotypic performance of these synthetic lines has rarely been assessed.
View Article and Find Full Text PDFEarly manifestations of neurodevelopmental copy number variants in children: A population-based investigation.
Biol Psychiatry
March 2025
Wolfson Centre for Young People's Mental Health, Cardiff University; Centre for Neuropsychiatric Genetics and Genomics, Cardiff University. Electronic address:
Background: There is clinical interest in recognising copy number variants (CNVs) in children as many have immediate and long-term health implications. Neurodevelopmental CNVs are associated with intellectual disability, autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), conditions typically diagnosed by medical practitioners. However, neurodevelopmental CNVs may have additional, early developmental impacts that have yet to be examined in unselected populations.
View Article and Find Full Text PDFMultidisciplinary assessment of the impact of assisted reproductive techniques on pregnancy and long-term outcomes of mother and child: Foundation of the LE-REP (Leipzig Reproductive Health) Center.
J Reprod Immunol
March 2025
Institute Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Medical Faculty, Leipzig University, Leipzig, Germany; Leipzig Reproductive Health Research Center (LE-REP), Leipzig University, Leipzig, Germany. Electronic address:
About 8-10 % of all people of reproductive age are unable to conceive children. In recent years, an increased number of consultations for fertility treatments has been observed with a continuing positive trend. It is known that infertility itself and assisted reproductive technologies (ARTs) are frequently associated with recurrent miscarriages, pregnancy complications or psychosocial problems.
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