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Introduction: Transposition of the great arteries (TGA), especially with intact ventricular septum (TGA-IVS), presents unique challenges during fetal-to-neonatal transition, which can contribute to developing persistent pulmonary hypertension of the newborn (PPHN).

Case Presentation: A male newborn with TGA-IVS, delivered via caesarean section, presented with hypoxemia and tachycardia immediately after birth (preductal SpO: 50-60%, post-ductal SpO: 70-75%). Echocardiography revealed a floppy interatrial septum and two interatrial connections with bidirectional shunting.

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Background: The development of new trans-septal transcatheter interventions for patients with structural heart disease necessitates a precise and comprehensive understanding of the anatomy of the interatrial septum (IAS). The scarcity of gross anatomical studies has triggered our interest in exploring the morphometry and morphology of IAS.

Aims: To study the morphology, morphometry and variations of the interatrial septum in autopsied human hearts.

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Inter-atrial Septum Stenting in Congenital Heart Disease Patient: A Case Series in Indonesia.

Cardiovasc Hematol Disord Drug Targets

November 2024

Division of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, Indonesia.

Background: Inter-atrial septum (IAS) stenting in duct-dependent congenital heart disease patient has shown to be an effective way to maintain inter-atrial blood flow, however it is still considered a high risk procedure and inter-atrial septum stenting remains a low-frequency procedure.

Method: A single-center observational cohort study was carried out at the National Cardiovascular Center Harapan Kita (NCCHK) between April 2019 and April 2023. This study included duct-dependent congenital heart disease patients.

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Article Synopsis
  • Surgeons often leave a residual atrial-level communication during Tetralogy of Fallot (TOF) repairs, and this study aimed to see how closing this communication affects patient recovery.
  • The researchers reviewed records of 132 TOF patients who had surgery before 12 months old, comparing outcomes between those with and without the communication.
  • The results showed no significant differences in key recovery metrics like cardiac output, drug therapy duration, or intensive care stay, suggesting that closing the communication doesn't significantly alter short-term or mid-term recovery outcomes.
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