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Understanding the Dual Role of Macrophages in Tumor Growth and Therapy: A Mechanistic Review.
Chem Biodivers
January 2025
Faculty of Chemistry and Life Sciences, Department of Chemistry, Government College University Lahore, Lahore, Pakistan.
Macrophages are heterogeneous cells that are the mediators of tissue homeostasis. These immune cells originated from monocytes and are classified into two basic categories, M1 and M2 macrophages. M1 macrophages exhibit anti-tumorous inflammatory reactions due to the behavior of phagocytosis.
View Article and Find Full Text PDFextracts mediated synthesis of copper oxide nanoparticles and their biological applications.
Heliyon
January 2025
Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia.
With the passage of time there is enormous development in the field of science and technology, however, human health remained the utmost concern. There are different strategies that helps us to treat various diseases but they have adverse reactions on our bodies. Nanobiotechnology is the advanced field consisting of new techniques and fabrication procedures for nanostructures for making drugs more effective against diseases in less time.
View Article and Find Full Text PDFGelatin Multiwalled Carbon Nanotube Composite 3D Printed Semi Biological Mesh for Abdominal Hernia Treatment.
Chem Asian J
January 2025
Indian Institute of Technology Ropar, Biomedical Engineering, Department of Biomedical Engineering, IIT Ropar, Main Campus, India, 140001, Ropar, INDIA.
Hernia is characterized by the protrusion of organs or tissue through weakened areas in the abdominal cavity wall. A common treatment for hernia involves the implantation of a mesh which promotes the growth of new tissue around or within the implanted material in the damaged area. The mesh is typically made from synthetic materials like polypropylene.
View Article and Find Full Text PDFApplication of Light-Responsive Nanomaterials in Bone Tissue Engineering.
Pharmaceutics
January 2025
Department of Orthopedics, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gongwei Road, Pudong, Shanghai 201300, China.
The application of light-responsive nanomaterials (LRNs) in bone tissue engineering shows broad prospects, especially in promoting bone healing and regeneration. With a deeper understanding of the mechanisms of bone defects and healing disorders, LRNs are receiving increasing attention due to their non-invasive, controllable, and efficient properties. These materials can regulate cellular biological reactions and promote bone cell adhesion, proliferation, and differentiation by absorbing specific wavelengths of light and converting them into physical and chemical signals.
View Article and Find Full Text PDFNanoformulation of Polymyxin E Through Complex Coacervation: A Pharmacokinetic Analysis.
Pharmaceutics
January 2025
Center for Pharmacy, University of Bergen, 5020 Bergen, Norway.
Polymyxin E (PME), a polymyxin antibiotic, serves as a final resort against antibiotic resistance. Nephrotoxicity is the primary concern when employing PME. To alleviate this issue, researchers have explored strategies including dosing adjustments and innovative formulations.
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