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Clinical Insights on My Acute Ischemic Stroke Caused by a Carotid Web.
Cureus
December 2024
Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Acute ischemic stroke, a medical emergency caused by reduced cerebral blood flow, results in brain cell damage. While commonly associated with older individuals, strokes can also occur in young and middle-aged adults, posing significant socio-economic and health challenges due to the long-term impact of the condition. This poses significant socio-economic and health challenges because stroke is a leading cause of disability and mortality.
View Article and Find Full Text PDFImpact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.
Front Neurol
January 2025
Department of Emergency Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Introduction: The COVID-19 pandemic is known to impact in-hospital processes for acute stroke patients, potentially resulting in delays due to quarantine and screening measures. The purpose of this study was to determine effects of changes in in-hospital quarantine policies on quality of care for acute stroke patients.
Methods: Hyperacute ischemic stroke patients who were admitted to Korea University Guro Hospital between January 2019 and February 2021 via the emergency department were included in this study.
Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases.
F1000Res
January 2025
German Centre for the Protection of Laboratory Animals (Bf3R), German Federal Institute for Risk Assessment (BfR), Berlin, Berlin, Germany.
The translation of animal-based biomedical research into clinical research is often inadequate. Maximizing translation should be central to animal research on human diseases, guiding researchers in study design and animal model selection. However, practical considerations often drive the choice of animal model, which may not always reflect key patient characteristics, such as sex and age, impacting the disease's course.
View Article and Find Full Text PDFThe role of mitochondrial reactive oxygen species in initiating mitochondrial damage and inflammation in wasp-venom-induced acute kidney injury.
J Toxicol Pathol
January 2025
Department of Nephrology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441000, China.
Acute kidney injury induced by stings from multiple wasps is a medical emergency and is a driving factor of acute renal dysfunction. Numerous studies have shown that mitochondrial reactive oxygen species (mtROS) play a key role in ischemia-reperfusion injury-, cisplatin-, and sepsis-induced acute kidney injury. However, the role of mtROS and its underlying mechanisms in wasp-venom-induced acute kidney injury remain inconclusive.
View Article and Find Full Text PDFDifferent effects of mechano- and metaboreflex on the central blood pressure waveform.
Front Physiol
January 2025
Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan.
Introduction: The effect of mechanoreflex on central blood pressure (BP) is unclear, although the influence of metaboreflex has been investigated. A relatively small contribution of the mechanoreflex to the pressor response to exercise has been considered in humans because many studies have failed to isolate the mechanoreflex-mediated pressor response. In a recent study, we successfully isolated a mechanoreflex-mediated pressor response using static passive stretching (SPS) in the forearm.
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