31 patients with refractory enuresis underwent simultaneous urethrocystometry. Pure urethral instability was encountered in 14, urethral and bladder instability in 11 and isolated uninhibited bladder in 3. This allows us to discuss the functional relationship between the urethra and the bladder. We consider urethral instability as being a trigger mechanism for detrusor contraction, and the explanation for the paradox of stable bladder enuresis. Phenylpropanolamine (Ornade), 25-50 mg at bedtime, stabilizes the vesicosphincteric unit and stopped bedwetting in 11 of 16 patients.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000463819DOI Listing

Publication Analysis

Top Keywords

urethral instability
12
enuresis urethral
4
instability
4
instability patients
4
patients refractory
4
refractory enuresis
4
enuresis underwent
4
underwent simultaneous
4
simultaneous urethrocystometry
4
urethrocystometry pure
4

Similar Publications

Introduction: Posterior urethral valve (PUV) is a major cause of congenital bladder dysfunction, often persisting despite treatment. Emerging therapies, including anticholinergics and α-1 blockers, offer potential but lack clear guidelines. This study evaluates their effectiveness in improving bladder function after valve fulguration.

View Article and Find Full Text PDF

Purpose: This study investigates a real-world multicenter cohort of patients with urinary tract cancer (UTC), with primary disease sites including the bladder, urethra, and upper tract, who enrolled for research molecular testing of their germline and tumor. The purpose of this study was to evaluate factors that could affect the likelihood of identifying a clinically actionable germline pathogenic variant (PV).

Methods: Patients with UTC were identified from 10 cancer institutes of the Oncology Research Information Exchange Network consortium.

View Article and Find Full Text PDF

Genital self-mutilation in psychiatric patients: A case report.

Int J Surg Case Rep

June 2024

Department of Urology, Cheikh Khalifa International University Hospital, Mohammed VI University of Sciences and Health (UM6SS), Casablanca, Morocco.

Introduction: Genital self-mutilation presents significant surgical challenges, particularly when complicated by psychiatric disorders. This case highlights the critical role of surgical intervention in the management of self-inflicted severe penile injuries and underscores the need to integrate surgical and psychiatric care to optimise results.

Case Presentation: A 43-year-old man, with progressive psychiatric issues, self-inflicted penile amputation.

View Article and Find Full Text PDF

Urethral stricture caused by various reasons has threatened the quality of life of patients for decades. Traditional reconstruction methods, especially for long-segment injuries, have shown poor outcomes in treating urethral strictures. Tissue engineering for urethral regeneration is an emerging concept in which special designed scaffolds and seed cells are used to promote local urethral regeneration.

View Article and Find Full Text PDF

"A successful reconstruction of remnants of corporal bodies and penile urethra after Total Glans Penis amputation following surgical circumcision in a 5-year-old boy". A case report and literature review.

Int J Surg Case Rep

February 2024

Department of Surgery, School of Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Department of Surgery, Muhimbili National Hospital, Dar es Salaam, Tanzania.

Introduction And Importance: Circumcision is the most common surgical procedure done in boys. Its complication varies from minor to severe. In most of African countries circumcision is often performed by traditional circumcisers.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!