Following two cases of anaphylactoid reactions during anaesthesia, immunoallergological investigations showed up the responsibility of droperidol, which probably acted by way of an anaphylactic mechanism. In both cases, there were no cardiovascular signs, the main clinical symptom being bronchospasm. The exceptional nature of allergic accidents due to neuroleptic drugs, as opposed to extrapyramidal phenomena, must be underlined. However, these reactions should cast doubts on the safety and usefulness of neuroleptanalgesia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0750-7658(84)80142-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anaphylactic shock is a severe, potentially life-threatening systemic allergic reaction. It can involve multiple organ systems and is triggered by medication, food, or insect stings. Epidemiological data vary due to differing definitions, but studies estimate that 0,26% of hospital admissions are due to anaphylaxis, with 1-3 deaths per million annually.
View Article and Find Full Text PDFRecommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).
Allergol Select
March 2025
Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history.
View Article and Find Full Text PDFUsefulness of gibberellin-regulated protein specific IgE measurement in patients with systemic symptoms of apple allergy with exercise.
J Dermatol
March 2025
Department of Pediatrics, Fujita Health University, Bantane Hospital, Aichi, Japan.
Patients with peach allergy who experience severe symptoms, including anaphylaxis, reportedly have a higher positivity for peach gibberellin-regulated protein (GRP)-specific immunoglobulin (Ig) E than those with only oral symptoms. However, a study in Italy investigating apple allergy (another Rosaceae fruit) found no clear association between apple GRP-specific IgE levels and clinical disease types. This study aimed to evaluate the clinical utility of GRP-specific IgE measurement in Japanese patients with apple allergy.
View Article and Find Full Text PDFIntroduction: The pathogenesis of cold urticaria (ColdU) and cold-induced anaphylaxis (ColdA) remains poorly understood, and ColdA is underrepresented in anaphylaxis literature. Laboratory features to guide management are largely unknown. This study evaluated basal serum tryptase (BST) and total immunoglobulin E (IgE) levels in ColdU and ColdA, their associations with clinical features, and the utility of testing for the p.
View Article and Find Full Text PDFACOEM Guidance Statement: Laboratory Animal Allergy.
J Occup Environ Med
February 2025
From the American College of Occupational and Environmental Medicine, Elk Grove Village, Illinois. Address correspondence to: Julie Ording, MPH, ACOEM, 25 Northwest Point Blvd, Suite 700, Elk Grove Village, IL 60007, 847/818-1800,
Ranging from mild respiratory allergy to anaphylaxis, laboratory animal allergy (LAA) can adversely affect an individual's health and career. LAA can be prevented through a hierarchy of controls. However, workers remain at risk as many, if not most, workplaces haven't fully adopted needed prevention practices.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!