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BMJ Open Respir Res
January 2025
CHU de Bordeaux, Bordeaux, France.
Background: Chronic obstructive pulmonary disease (COPD) is a common treatable disease often diagnosed in patients with risk factors after a prolonged period with suggestive symptoms. Our qualitative study aimed to identify barriers to establishing diagnosis in the natural history of this condition.
Methods: An inductive thematic analysis was performed on structured interviews with patients, general practitioners (GPs) and pulmonologists in France.
PLoS Med
January 2025
Clinical Epidemiology Unit, Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden.
Background: Cardiovascular, respiratory, and musculoskeletal disease are among the leading causes of disability in middle-aged and older people. Health and lifestyle factors in youth have known associations with cardiovascular or respiratory disease in adulthood, but largely unknown associations with musculoskeletal disease.
Methods And Findings: We included approximately 40,000 18-year-old Swedish males, who completed their conscription examination in 1969 to 1970, followed up until age of 60 years.
Am Fam Physician
January 2025
University of Kansas Medical Center, Kansas City.
Acute rhinosinusitis causes more than 30 million patients to seek health care per year in the United States. Respiratory tract infections, including bronchitis and sinusitis, account for 75% of outpatient antibiotic prescriptions in primary care. Sinusitis is a clinical diagnosis; the challenge lies in distinguishing between the symptoms of bacterial and viral sinusitis.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Department of Pediatrics, Zhejiang University School of Medicine Second Affiliated Hospital Jiashan Branch, the First People's Hospital of Jiashan, Jiashan, Zhejiang, 314100, People's Republic of China.
Although infection with is generally self-limited, it may cause refractory or life-threatening pneumonia with pulmonary or extrapulmonary complications. Necrotizing bronchitis is a rare condition with a high mortality rate. The present report describes a patient with mycoplasma pneumonia and necrotizing bronchitis that caused airway obstruction.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Research Unit of Biomedicine and Internal Medicine, University of Oulu, 902 20 Oulu, Finland.
Mucins 5AC (MUC5AC) and 5B (MUC5B) are the major mucins providing the organizing framework for the airway's mucus gel. We retrieved bronchial mucosal biopsies and bronchial wash (BW) samples through bronchoscopy from patients with chronic obstructive pulmonary disease ( = 38), healthy never-smokers ( = 40), and smokers with normal lung function ( = 40). The expression of MUC5AC and MUC5B was assessed immunohistochemically.
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