Veins and lymph ducts are closely linked anatomically, embryologically and physiologically. It is therefore not surprising that such a close relationship should reemerge in the pathology of each. Post-phlebitic disorders provide a classic example of this. Microlymphography, using fluorescence, and isotopic phlebolymphography produce positive, unequivocable arguments for the contribution of lymph to the genesis of post-phlebitic disorders; these methods are better than direct lymphology which is technically difficult and not altogether without its dangers. These findings should, of course, have bearing on therapy.
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Thromb Res
June 2024
Université Paris Cité, Innovative Therapies in Haemostasis, INSERM, 75006 Paris, France; F-CRIN INNOVTE, Saint-Étienne, France; Hematology Department, Assistance Publique Hôpitaux de Paris, 75015 Paris, France.
Background: Post-thrombotic syndrome (PTS) is the main long-term complication of deep vein thrombosis (DVT). Several therapies are being evaluated to prevent or to treat PTS. Identifying the patients most likely to benefit from these therapies presents a significant challenge.
View Article and Find Full Text PDFJ Vasc Surg Venous Lymphat Disord
November 2023
Division of Vascular and Endovascular Surgery, Duke University School of Medicine, Durham, NC. Electronic address:
Objective: Chronically indwelling inferior vena cava filters (IVCFs) can have multiple adverse sequelae, including IVCF-associated thrombosis. The Inari ClotTriever and FlowTriever mechanical and aspiration thrombectomy systems (Inari Medical) can be used for acute caval thrombosis associated with IVCFs if appropriate proximal IVCF protection is used intraprocedurally. The present study reports a single institution's outcomes after ClotTriever and FlowTriever thrombectomy of acute IVCF-associated iliocaval thrombus.
View Article and Find Full Text PDFFront Cardiovasc Med
February 2022
Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University, Wroclaw, Poland.
Importance: The post-thrombotic syndrome (PTS) is the most common long-term complication of deep vein thrombosis (DVT), occurring in up to 40-50% of cases. There are limited evidence-based approaches for PTS clinical management.
Objective: To provide an expert consensus for PTS diagnosis, prevention, and treatment.
Ann Vasc Surg
October 2021
Department of Surgery, Division of Vascular Surgery, Emory University Hospital, Atlanta, GA; Department of Surgery, Division of Vascular Surgery, Grady Health, Atlanta, GA. Electronic address:
Background: Chronic venous insufficiency (CVI) encompasses a myriad of clinical manifestations including lower extremity swelling and pain, ulcerations and chronic skin changes such as stasis dermatitis, and lipodermatosclerosis. CVI effects greater than 25 million Americans and has a significant socioeconomic and psychosocial impact. Treatment of CVI varies depending on the etiology.
View Article and Find Full Text PDFJ Vasc Surg
January 2013
Academic Section of Vascular Surgery, Department of Surgery & Cancer, Imperial College School of Medicine, Charing Cross Hospital, London, United Kingdom.
Objective: To assess each of the scoring systems used to diagnose and classify post-thrombotic syndrome, a common chronic complication of deep vein thrombosis. The design of the study was a systematic review of the literature pertaining to post-thrombotic syndrome.
Methods: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines by a search of PubMed (1948 to September 2011) using the search terms "post-thrombotic syndrome," "postthrombotic syndrome," "post-phlebitic syndrome," and "postphlebitic syndrome.
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