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Plasma Extracellular Matrix Protein 2 Level as a Predictive Biomarker for Rupture of Small Intracranial Aneurysms.
J Mol Neurosci
March 2025
Institute of Neurology, General Hospital of Northern Theater Command, Shenyang, 110016, Liaoning, China.
As the neuroimaging technology improves, the detection rate of unruptured intracranial aneurysms (UIA) is gradually increasing. However, there is currently no effective means to evaluate and predict the risk of rupture for small intracranial aneurysm (sIA, diameter < 7 mm). We previously identified extracellular matrix protein 2 (ECM2) as a potential candidate biomarker for predicting intracranial aneurysm (IA) rupture through iTRAQ combined with LC-MS/MS protein quantification technology, so this study aimed to further validate the ability of plasma ECM2 expression levels to predict IA rupture.
View Article and Find Full Text PDFSegmental arterial mediolysis with subarachnoid hemorrhage following chronic internal carotid artery dissection: illustrative case.
J Neurosurg Case Lessons
March 2025
Department of Neurosurgery, Chuno Kosei Hospital, Seki, Japan.
Background: Segmental arterial mediolysis (SAM) is a rare, noninflammatory vascular disease primarily affecting small to medium arteries. Although neurological presentations like subarachnoid hemorrhage (SAH) and ischemic stroke have been reported, awareness of SAM in neurology remains limited. The authors present a unique case of SAM with SAH following chronic internal carotid artery (ICA) dissection and explore the clinical course and potential ethnic implications of the disease.
View Article and Find Full Text PDFDelayed presentation and rupture of an intracranial pseudoaneurysm following penetrating trauma: illustrative case.
J Neurosurg Case Lessons
March 2025
Division of Neurological Surgery, Highland Hospital, Oakland, California.
Background: Pseudoaneurysms are rare vascular lesions that can form following injury to an artery. Damage to the artery can result in a hematoma surrounded by a layer of coagulation products. Intracranial pseudoaneurysms are particularly uncommon, comprising less than 1% of all aneurysms, and are often associated with traumatic brain injuries.
View Article and Find Full Text PDFMethods of Monitoring Intracranial Pressure: A Review.
Neurosurg Clin N Am
April 2025
Department of Neurosurgery, University of Illinois Chicago, Chicago, IL, USA. Electronic address:
Monitoring intracranial pressure (ICP) is important in a variety of neurologic conditions, including aneurysmal subarachnoid hemorrhage and traumatic brain injury. Monitoring and controlling ICP can mitigate secondary injury of the brain. Of the invasive methods of monitoring ICP, the external ventricular drain is still considered the gold standard.
View Article and Find Full Text PDFInfluencing factors of health promotion behaviour in patients with aortic dissection: a qualitative study using the COM-B model.
BMJ Open
March 2025
Department of Cardiac Surgery Nursing, Fujian Medical University Union Hospital, Fuzhou, China
Objectives: This study aimed to understand influencing factors of health promotion behaviour in patients with aortic dissection (AD) using the capability, opportunity, motivation, behaviour (COM-B) model of behaviour.
Design: A descriptive qualitative design was adopted. Data were collected using face-to-face semi-structured interviews and analysed using directed content analysis.
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