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Outcomes Associated With Blastomycosis in Solid Organ and Hematopoietic Cell Transplant Recipients.
Transpl Infect Dis
December 2024
Department of Medicine, Section of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Introduction: With reports of expanding epidemiology of blastomycosis across the United States, the purpose of this study was to evaluate the incidence and outcomes associated with blastomycosis in solid organ transplant (SOT) and hematopoietic cell transplant (HCT) recipients.
Methods: We conducted a retrospective case series of adult SOT and HCT recipients at a tertiary care medical center between January 1, 2005 and September 30, 2023. Cases were defined as culture-proven blastomycosis.
An Unusual, Symmetric Rash on Both Forearms in a 94-Year-Old Patient A Clinicopathological Challenge and Diagnostic Pitfall.
J Cutan Pathol
February 2025
Department of Dermatology, University Hospital Basel, Basel, Switzerland.
Article Synopsis
- Trichophyton rubrum (T. rubrum) typically causes minor skin infections, mostly affecting healthy individuals, but can lead to serious infections in immunocompromised patients.
- A unique case involved a 94-year-old man with an invasive T. rubrum infection on both forearms, which resembled cutaneous blastomycosis.
- Diagnosis is complicated as T. rubrum can present with large spore-like structures that mimic Blastomyces dermatitidis, underscoring the necessity for culture or PCR testing for accurate identification.
Article Synopsis
- - A study was done on a cluster of blastomycosis cases affecting both humans and dogs in a Wisconsin neighborhood.
- - Researchers interviewed residents and gathered blood samples to test for Blastomyces antibodies using enzyme immunoassay techniques.
- - While no clear cause was identified, possible exposure sources include the nearby riverbank, trails, yards, or dust from construction activities.
Blastomyces spp. fungi, the causal agent of blastomycosis, are common in North America but do occur in other areas of the world. The most prevalent pathogen in the genus is B.
View Article and Find Full Text PDFExome Sequencing of a Blastomycosis Case-Control Cohort From Manitoba and Northwestern Ontario, Canada.
Mycoses
September 2024
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Background: Blastomycosis is a pulmonary disease caused by Blastomyces spp., a group of pathogenic dimorphic fungi endemic to a number of geographic regions, specifically Manitoba and northwestern Ontario, Canada. Immunosuppression is a major risk factor affecting disease susceptibility, yet host immunity is not well understood.
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