Lipid peroxidation was studied in the course of the development of anoxic injury to the mitochondria in vitro. Hydrolysis of mitochondial phospholipids was accompanied by an increase in antioxidant activity (AOA) of the organelles. At the same time the ability to transoxidation in liposomes formed from lipids extracted from the injured mitochondria was discovered to be increased. It is assumed that AOA of the mitochondria rises at the expense of antioxidants not extractable with a mixture of chloroform and methanol.
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