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Multiorgan Involvement: Is There a Relevant Pathogenetic Link?
J Assoc Physicians India
December 2024
Head of Department, PSG Institute of Medical Sciences & Research, Coimbatore, Tamil Nadu, India.
Multisystem autoimmune disorders have different presenting symptoms with organ involvement phased over numerous years. We have a 56-year-old homemaker who is a known case of Graves' disease-post-thyroidectomy performed 20 years ago-and developed a volume overload state with exertional dyspnea for a period of 1.5 years.
View Article and Find Full Text PDFAtrial fibrillation in young stroke patients: Associated factors and outcomes in a nationwide analysis.
Eur J Neurol
January 2025
Department of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.
Background And Purpose: Knowledge about the prevalence of atrial fibrillation (AF) in young stroke patients, as well as its associated factors and outcomes, is scarce. Our objective was to analyse it.
Methods: A retrospective analysis of the Spain Nationwide Minimum Basic Data Set (MBDS) (2016-2020), including ischaemic stroke (IS) patients aged 18 and 50 years, was conducted.
Prevalence and Risk Factors of Heart Failure in Patients Diagnosed with Hyperthyroidism: A Systematic Review and Meta-analysis.
touchREV Endocrinol
October 2024
Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Article Synopsis
- Hyperthyroidism significantly affects the cardiovascular system, leading to conditions like thyrotoxic cardiomyopathy, which can cause heart failure.
- A study analyzed 30,889 patients to find that the overall prevalence of heart failure in those with hyperthyroidism is 8%.
- Key risk factors for developing heart failure in these patients include atrial fibrillation, chronic kidney disease, anemia, hypertension, and a history of stroke or coronary artery disease.
Pancytopenia, Cholestatic Jaundice, and Pulmonary Hypertension: Rare Extrathyroidal Manifestations of Graves' Disease.
Cureus
October 2024
Endocrinology, Hospital Sultanah Aminah, Johor Bahru, MYS.
Pancytopenia, cholestatic jaundice, and pulmonary hypertension are rare but serious complications of thyrotoxicosis. It is uncommonly seen in patients with hyperthyroidism and may result in treatment-related dilemmas as bone marrow suppression and drug-induced liver injury are known complications of anti-thyroid treatment. We describe a case of Graves' disease presenting with all three manifestations of pancytopenia, cholestatic jaundice, and pulmonary hypertension during a relapse of thyrotoxicosis.
View Article and Find Full Text PDFSex- and age-specific differences in the use of antiarrhythmic therapies among atrial fibrillation patients: a nationwide cohort study.
Europace
October 2024
Jorvi Hospital, Department of Internal Medicine, HUS Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Article Synopsis
- Atrial fibrillation (AF) patients often need rhythm control therapy, and the study explored whether there are gender disparities in the use of antiarrhythmic therapies (AATs) among these patients in Finland from 2007-2018.
- Out of 229,565 patients studied, women were older, had different health profiles compared to men, and were treated with AATs less frequently, with 17.6% of women and 25.1% of men receiving treatment.
- Interestingly, while women received antiarrhythmic drugs more often across all ages, they underwent fewer cardioversion and ablation procedures, especially those under 65 years old.
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