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Effects of denosumab and zoledronic acid on postmenopausal osteoporosis, bone density, and fat-free mass.

Arch Osteoporos

January 2025

Division of Endocrinology & Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Unlabelled: This study compared denosumab and zoledronic acid for treating osteoporosis in drug-naïve postmenopausal Korean women. Over 3 years, both drugs significantly increased bone mineral density. However, denosumab also improved fat-free mass, suggesting it may be a better initial treatment for osteoporosis with low muscle mass, assuming all other conditions remain constant.

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Purpose Of Review: Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals with many modern applications, leading to widespread contamination and universal human exposure. PFAS exposure during early life is of particular concern, given susceptibility of the developing fetal and infant brain to toxic exposures. This review aims to synthesize current evidence, discuss methodological challenges, and highlight research gaps to guide future studies on the impact of PFAS on neurodevelopment.

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Purpose: Recovery is a key objective in mental health services for people with severe mental illness (SMI). In addition to clinical and functional recovery, personal recovery has gained increasing attention. The CHIME Framework identifies five personal recovery processes-Connectedness, Hope, Identity, Meaning, Empowerment-and is the theoretical foundation for the Brief INSPIRE, a validated Patient-Rated Experience Measure (PREM) to evaluate recovery support.

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Objectives: Sharing micro-computed tomographic (μCT) scans of teeth increases data accessibility and reduces the need for repeated scans of any given specimen. However, the use of the same TIFF stacks or DICOMs by multiple individuals has the potential to introduce new sources of error. Here, we explore whether use of the same μCT scans by different persons produces comparable results.

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Background: Dementia is one of the most pressing health concerns among the ageing population, imposing significant health, financial and caregiving burdens on people with dementia (PWD), their families and caregivers. Building the capacity of nursing students is essential for effectively improving quality of life for affected people. This study aimed to assess nursing students' knowledge and attitudes toward dementia and its associated factors.

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