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Bioengineered Silk Fibroin Hydrogel Reinforced with Collagen-Like Protein Chimeras for Improved Wound Healing.
Macromol Biosci
October 2024
Department of Biochemistry and Biotechnology, CSIR- Central Leather Research Institute, Chennai, 600020, India.
Article Synopsis
- - The study explores a new hydrogel made from natural silk fibroin and a customizable collagen-like protein, designed for better wound repair through rapid crosslinking using light and a photo-initiator.
- - This engineered hydrogel, called PASCH, shows superior stability and biological properties compared to control hydrogels made solely from silk fibroin.
- - It promotes better cell adhesion and growth in lab tests, leads to enhanced wound closure in endothelial cells, and supports cell repair through various cytokines and growth factors, highlighting its potential for tissue engineering.
Arabinoxylan from pearl millet bran: Optimized extraction, structural characterization, and its bioactivities.
Int J Biol Macromol
November 2024
Department of Traditional Foods and Applied Nutrition, CSIR-Central Food Technological Research Institute, Mysore 570020, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:
Arabinoxylan (AX) from cereals and millets have garnered attention due to the myriad of their bioactivities. Pearl millet (Pennisetum glaucum) bran, an underexplored milling by-product was used to extract AX (PMAX) by optimized alkali-assisted extraction using Response Surface Methodology and Central Composite Design, achieving a yield of 15.96 ± 0.
View Article and Find Full Text PDFNovel Properties of Old Propranolol-Assessment of Antiglycation Activity through and Approaches.
ACS Omega
June 2024
Department of Hygiene, Epidemiology and Ergonomics, Medical University of Bialystok, 2c Mickiewicza Street, Bialystok 15-233, Poland.
Hypertension has earned the "silent killer" nickname since it may lead to a number of comorbidities, including diabetes and cardiovascular diseases. Oxidative stress and protein glycation play vital roles in the pathogenesis of hypertension. Several studies have shown that they profoundly account for vascular dysfunction, endothelial damage, and disruption of blood pressure regulatory mechanisms.
View Article and Find Full Text PDFEffects of Edible Organic Acid Soaking on Color, Protein Physicochemical, and Digestion Characteristics of Ready-to-Eat Shrimp upon Processing and Sterilization.
Foods
January 2024
State Key Laboratory of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Soft-packed ready-to-eat (RTE) shrimp has gradually become popular with consumers due to its portability and deliciousness. However, the browning caused by high-temperature sterilization is a non-negligible disadvantage affecting sensory quality. RTE shrimp is processed through "boiling + vacuum soft packing + high temperature and pressure sterilization".
View Article and Find Full Text PDFPreliminary evaluation of the antiglycoxidant activity of verapamil using various and biochemical/biophysical methods.
Front Pharmacol
November 2023
Department of Hygiene, Epidemiology and Ergonomics, Medical University of Bialystok, Bialystok, Poland.
Glycoxidative stress is essential for linking glucose disturbances and cardiovascular diseases. Unfortunately, contemporary antidiabetic drugs do not have an antiglycative effect but only lower blood glucose levels. Therefore, there is an intense search for substances that could inhibit protein glycation and prevent diabetic complications.
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