Three neonates with extreme edema associated with cardiovascular and renal insufficiency were treated with hemo-ultrafiltration for removal of critical edema fluid. In each patient peritoneal dialysis had not been effective in expedient fluid removal. Ultrafiltration was accomplished by occlusion of the proximal dialysate portal of a Travenol EX12-11, 0.8 m2 dialyzer and the application of vacuum suction to the distal portal. Blood flow ranged from 10-25 ml/min. The rate of ultrafiltration averaged 0.57 ml/kg/min resulting in losses of 4-16% of body weight. Episodes of hypotension were associated with too rapid ultrafiltration rate and not total volume removed. All patients tolerated the procedure. Two of the three patients demonstrated improvement in blood pressure, oxygenation and urine flow following the ultrafiltration. Ultrafiltration in the newborn may be a useful therapeutic procedure when conventional treatment fails.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Mesophilic anaerobic digestion of mixed sludge in CSTR and AnMBR systems: A perspective on microplastics fate.
J Environ Manage
January 2025
CALAGUA - Unitat Mixta UV-UPV, Departament d'Enginyeria Química, Universitat de València, Avinguda de la Universitat s/n, Burjassot, Valencia, 46100, Spain.
Most microplastics (MPs) end up in the biosolids produced in wastewater treatment plants (WWTPs) and can pose contamination risks when the biosolids are applied to agriculture. This study evaluated the impact of mesophilic anaerobic digestion on the fate of MPs in WWTP sludge. For this, two laboratory-scale anaerobic digesters were operated in parallel, consisting of a continuous stirred tank reactor (CSTR) and a membrane bioreactor (AnMBR) equipped with an ultrafiltration membrane to decouple the hydraulic and sludge retention times.
View Article and Find Full Text PDFThe influence of cardiopulmonary bypass residual volume processing technique on blood management in cardiac surgical patients.
Perfusion
January 2025
Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, USA.
Post-cardiopulmonary bypass (CPB) blood processing is an important component of blood management during cardiac surgery. The purpose of this study is to evaluate several methods of processing post-CPB residual blood. Using a multi-institutional national database (SpecialtyCare Operative Procedural rEgistry [SCOPE]), 77,591 cardiac surgical operations performed in adults (>18 years) between January 2017 and September 2022 were reviewed.
View Article and Find Full Text PDFRetention mechanism in slalom chromatography: Perspectives on the characterization of large DNA and RNA biopolymers in cell and gene therapy.
J Chromatogr A
January 2025
Waters Corporation, Instrument/Core Research/Fundamental, Milford, MA, 01757, USA. Electronic address:
Significant progress has been made in the last two decades in producing small (<2μm), high-purity, and low-adsorption particles, columns and system hardware, for ultra-high pressure liquid chromatography (UHPLC). Simultaneously, the recent rapid expansion of cell and gene therapies for treating diseases necessitates novel analytical technologies for analyzing large (>2 kbp) plasmid double-stranded (ds) DNA (which encodes for the in vitro transcription (IVT) of single-stranded (ss) mRNA therapeutics) and dsRNAs (related to IVT production impurities) biopolymers. In this context, slalom chromatography (SC), a retention mode co-discovered in 1988, is being revitalized using the most advanced column technologies for improved determination of the critical quality attributes (CQAs) of such new therapeutics.
View Article and Find Full Text PDFDetections of Chemicals and Migratory Plastics in Peritoneal Dialysis Fluids.
Indian J Nephrol
July 2024
Department of Chemical Engineering, Indian Institute of Technology, Hyderabad, Tarnaka, India.
Background: Peritoneal dialysis (PD) is an important modality of renal replacement therapy (RRT). Peritonitis and ultrafiltration failure are complications that have a long-term impact on PD patients. Besides touch contamination, procedural errors and clinical reasons of peritonitis, contaminants, and constituents of peritoneal dialysis fluids (PDFs) have been implicated in causing peritonitis and ultrafiltration failure.
View Article and Find Full Text PDFEvaluation of integrated polysaccharide, biopolymers and clay composite membranes for clarification process of citrus fruit (sweet lime) juice.
Int J Biol Macromol
January 2025
Advanced Membrane Technology Research Centre (AMTEC), Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia.
This study focuses on the development of an efficient membrane-based clarification process to enhance the performance of subsequent ultrafiltration and produce high-quality sweet lime juice. A range of casting solutions were prepared using a blend of pore-forming polymers, including polyvinylpyrrolidone (PVP), polyvinylidene fluoride (PVDF), and cellulose acetate (CA), dissolved in dimethylformamide (DMF) solvent through the phase inversion technique. To further enhance the membrane's performance, four biopolymers poly (lactic acid) (PLA), xanthan gum, chitosan, and gelatin were incorporated, with and without clay, to refine its structure, porosity, and surface properties.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!