In the Federal Republic of Germany, between 1971 and 1983, 365 women were by chance vaccinated against rubella (Cendehill or RA-27/3-HDC rubella live vaccine) between 3 months before and up to 3 months after conception. The data on these women are compared with similar ones from the USA (1096 women vaccinated with Cendehill, HPV77 or RA-27/3 vaccine within the same time-span in relation to pregnancy). The results indicate that the risk for the child from rubella vaccination of the mother before pregnancy and in the first trimester is minimal. Vaccination during early pregnancy is thus no compelling indication for the termination of pregnancy. However, known pregnancy continues to be a contraindication to rubella vaccination.
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http://dx.doi.org/10.1055/s-2008-1069458 | DOI Listing |
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