The Authors have examined the action of large doses of vitamin A (2000 U.I./Kg diet) compared with that obtained by administration of a lipid lowering drug (Tioadenolo) and a standard diet in albino rats feed at first an atherogenic diet for 15 days. The "recovering" diets were adminisetred for 15 and 30 days. Serum components were obtained with routine chemical-clinical assay, membrane lipids and related fatty acids by the method of Folch in erythrocytes isolated by the method of Wipple. Both retinol and Tioadenolo lower blood plasma and cell membrane lipids more than a standard diet.
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