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Successful endovascular treatment of a spontaneous bleeding accessory spleen: A case report.
Radiol Case Rep
July 2019
Interventional Radiology Department, AORN "A. Cardarelli", Via A. Cardarelli 9, 80131 Naples, Italy.
Accessory spleens are often encountered in radiologic studies and they are not usually associated with symptoms. They could arise from autotransplantation of splenic tissue after splenic trauma or splenectomy (splenosis) [1]. In this case we describe a woman treated for splenectomy 20 years before and subsequently for adhesions, that suffered sudden left upper abdominal quadrant pain, weakness, and pale color.
View Article and Find Full Text PDFLight-chain deposition disease (LCDD) is a rare plasma cell neoplasm that secretes an abnormal immunoglobulin light chain, which is deposited in tissues, leading to organ dysfunction. Spontaneous splenic rupture is a rare and life-threatening complication of treatment with granulocyte colony-stimulating factor (G-CSF). Herein, we describe spontaneous splenic rupture after the administration of lenograstim to a patient with LCDD undergoing autologous stem cell transplantation (ASCT).
View Article and Find Full Text PDFThe spleen--a potential source of new islets for transplantation?
J Pediatr Surg
February 2008
Paediatric Surgical Research Laboratory, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, OX3 9DU Oxford, United Kingdom.
Background/purpose: Islet transplantation offers the potential to reverse diabetes soon after diagnosis and has achieved considerable success in adults. Its use in children has been limited by long-term immunosuppression requirements and donor pancreas shortages. An ideal alternative source of islets would be from autologous precursor cells.
View Article and Find Full Text PDFSuccessive cultures of mature hepatocytes for hepatocyte autotransplantation to assist liver function after liver resection for cancer.
Oncol Rep
January 2003
Department of Surgery, Shiga Medical Center for Adults, Moriyama City, Shiga 524, Japan.
We developed a method for the rapid successive cultures of adult rat mature hepatocytes on plastic dishes while avoiding viral transformation or co-culture with other cell lines. This method also allows for culturing adult human mature hepatocytes up to the secondary culture. These can be expected to provide a good source for hepatocyte autotransplantation, and, combined with the previously reported methods for the transplantation of hepatocytes into the spleen, a promising option for the support of liver function after liver resection for cancer without the need for immunosuppressive agents.
View Article and Find Full Text PDF[Autotransplantation of the traumatized spleen: a report of 20 cases].
Zhonghua Wai Ke Za Zhi
October 1985
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