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Effect of local ozone treatment on rats with anterior rectal resection and the possible mechanisms.
Biomed Eng Online
August 2021
National Center of Colorectal Surgery, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, No. 157 Daming Road, Qinhuai District, Nanjing, 210012, Jiangsu, China.
Background: Anterior resection syndrome (ARS) is characterized by the diverse and interchangeable evacuatory symptoms that may occur following distal colorectal resection. We aimed to investigate the effect and potential mechanisms of ozone perfusion on rats with anterior rectal resection (ARR).
Material And Methods: After establishment of rat ARR model, 20, 40 and 80 ug/ml ozone was used to treat rats by enema administration.
[Prevention and management of anterior resection syndrome].
Zhonghua Wei Chang Wai Ke Za Zhi
April 2016
Department of Colorectal Cancer Surgery, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University Cancer Hospital and Institute, Beijing 100142, China.
Because of the improvement of surgical technique and the widely use of multimodality therapy, more patients with rectal cancer undergo sphincter-preserving surgery. However, it has been reported that up to 90% of such patients will suffer from bowel dysfunction, ranging from increased bowel frequency to faecal incontinence or evacuatory dysfunction. This wide spectrum of symptoms after resection of the rectum has been termed anterior resection syndrome (ARS).
View Article and Find Full Text PDFSymptom distribution and anorectal physiology results in male patients with rectal intussusception and prolapse.
J Surg Res
May 2014
Academic Surgical Unit, Centre for Digestive Diseases, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University London, Whitechapel, London, UK.
Background: Rectal intussusception and external rectal prolapse are uncommon proctographic findings in men reflecting the lack of studies investigating such patients. The aim of this study was to identify the demographic, clinical, and physiological characteristics of this population with a view to appreciate the mechanism of development of this condition.
Methods: All men, presenting with symptoms of constipation or fecal incontinence, who were diagnosed proctographically with recto-rectal intussusception (RRI)/recto-anal intussusception (RAI) or external rectal prolapse (ERP) between 1994 and 2007 at a tertiary academic colorectal unit were studied.
Manometric evaluation of evacuatory difficulty (dyschezia) in ileal pouch patients.
Inflamm Bowel Dis
March 2013
Department of Gastroenterology/Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Article Synopsis
- The study investigates dyschezia in patients with ileal pouch-anal anastomosis, focusing on the role of paradoxical contractions as a potential contributing factor.
- A total of 45 patients were analyzed, with 10 in the functional pouch disorder (FPD) group and 35 in the inflammatory/structural pouch disorder (ISPD) group; no significant demographic differences were noted, but manometric evaluations revealed higher rates of paradoxical contractions in the FPD group.
- The findings indicate that dyschezia may have different underlying physiological causes depending on the type of pouch disorder present, highlighting the need for tailored clinical approaches.
Anterior resection syndrome.
Lancet Oncol
September 2012
Academic Surgical Unit, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Up to 80% of patients with rectal cancer undergo sphincter-preserving surgery. It is widely accepted that up to 90% of such patients will subsequently have a change in bowel habit, ranging from increased bowel frequency to faecal incontinence or evacuatory dysfunction. This wide spectrum of symptoms after resection and reconstruction of the rectum has been termed anterior resection syndrome.
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