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Body surface potential mapping detects early disease onset in plakophilin-2-pathogenic variant carriers.
Europace
July 2023
Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive inherited cardiac disease. Early detection of disease and risk stratification remain challenging due to heterogeneous phenotypic expression. The standard configuration of the 12 lead electrocardiogram (ECG) might be insensitive to identify subtle ECG abnormalities.
View Article and Find Full Text PDFECG-based techniques to enhance clinical practice in cardiac genetic disease management.
J Electrocardiol
January 2023
Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. Electronic address:
Introduction: Inherited cardiomyopathies are associated with a broad spectrum of potentially lethal phenotypes characterized by structural and electrical myocardial remodeling. Increased awareness and genetic cascade screening lead to more genotype-positive, yet phenotype-negative individuals to be evaluated and followed up. The predictive value of genetic testing is hampered by incomplete penetrance and high variability in disease onset, progression and severity.
View Article and Find Full Text PDFElectrocardiographic imaging (ECGI): What is the minimal number of leads needed to obtain a good spatial resolution?
J Electrocardiol
June 2021
Hospital Luz Lisboa, Av Lusiada 1500-650, Lisboa, Portugal.
Article Synopsis
- The study aimed to find out the minimum number of ECGI leads necessary for achieving good spatial resolution in mapping arrhythmias during ablation procedures.
- Out of 20 patients, the highest agreement between ECGI and Carto mapping was when using 23 electrode bands (85% agree rate), while reducing to 6 electrode bands significantly decreased agreement to 55%.
- The findings suggest that while fewer leads lead to lower spatial resolution, approximately 74 leads are sufficient for acceptable quality mapping, indicating efficiency in lead usage can be achieved without compromising accuracy.
Varied onset of heart ventricular depolarization in different age groups of healthy volunteers.
Physiol Res
December 2019
Institute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovak Republic.
Group mean isopotential maps of initial parts of ventricular depolarization (QRS complex) in 4 age groups (10, 14, 19 and 22 years) of young healthy subjects, females and males, were analyzed using different increments between isopotential lines. It was found that the increment 0.1 mV masks some features of the maps, which are seen only by smaller increment (0.
View Article and Find Full Text PDFDisturbances in intraventricular conduction in children with end-stage renal disease on peritoneal dialysis: A pilot study.
Adv Clin Exp Med
September 2018
Department of Pediatric Nephrology, Wroclaw Medical University, Poland.
Background: The progression of chronic kidney disease is accompanied by multi-organ disorders, among which cardiovascular diseases have the status of a serious clinical problem. The body surface potential mapping (BSPM) technique is a non-invasive method which enables the detection of pathological changes in the bioelectrical activity of the heart.
Objectives: The aim of this study was to identify possible disturbances in the intraventricular conduction system in peritoneally dialyzed children.
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