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Peripartum genital tuberculosis causing uterine scar dehiscence and secondary post-partum hemorrhage: Exceedingly rare yet alarmingly life threatening.
Med J Armed Forces India
December 2024
Professor (Obst & Gynae), All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Current Advances in Lipid-Based Drug Delivery Systems as Nanocarriers for the Management of Female Genital Tuberculosis.
Cureus
November 2024
Department of Pharmacology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Female genital tuberculosis (FGTB) arises from infection and can rarely be caused by or atypical mycobacteria. FGTB usually arises from tuberculosis (TB) that affects the lungs or other organs. The infection can enter the vaginal tract directly from abdominal TB or by hematogenous or lymphatic pathways.
View Article and Find Full Text PDFIncidental finding of isolated uterine cervix tuberculosis with successful management: A case report.
Int J Surg Case Rep
January 2025
Department of Internal medicine, Hawassa University Comprehensive Specialized Hospital, Hawassa, Sidama, Ethiopia.
Article Synopsis
- Cervical tuberculosis is rare, constituting only 0.1-0.65% of all tuberculosis cases, and presents primarily with symptoms like infertility, abnormal bleeding, pelvic pain, and amenorrhea, without any specific visible changes to the cervix.
- A 45-year-old woman was misdiagnosed with cervical cancer, but further examination revealed she actually had tuberculosis of the cervix, highlighting the importance of proper diagnosis.
- Tuberculosis can cause chronic pelvic inflammation and infertility, and clinicians should consider it as a potential diagnosis in cases of unexplained lower genital tract symptoms, since it can mimic more common conditions like cervical cancer.
Disseminated Tuberculosis Masquerading as a Uterine Cervical Mass in an Immunocompetent Young Female: A Case Report.
Cureus
October 2024
Internal Medicine, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Concurrent tubercular involvement of two or more non-contiguous organs is termed disseminated tuberculosis (TB) and is rare in immunocompetent patients. We describe the case of a young immunocompetent woman with disseminated TB who presented with primary complaints of amenorrhea and dysuria. Abdominal ultrasound showed a uterine cervical mass, which on histopathological evaluation revealed epithelioid granulomata with Langhans giant cells and acid-fast bacilli (AFB).
View Article and Find Full Text PDFPhase II study of enlonstobart (SG001), a novel PD-1 inhibitor in patients with PD-L1 positive recurrent/metastatic cervical cancer.
Gynecol Oncol
December 2024
Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:
Background: Platinum-based chemotherapy with or without bevacizumab is the first-line treatment for patients with recurrent or metastatic cervical cancer (r/mCC), and the treatment options are limited for r/mCC after first-line treatment. Enlonstobart (SG001) is a fully humanized and high-affinity anti-PD-1 immunoglobulin G4 monoclonal antibody. Previous phase Ib study demonstrated that SG001 had a promising efficacy in patients with PD-L1 positive r/mCC.
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