Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
The effect of reumycin, an antitumor antibiotic on the peripheral circulatory system and bone marrow was studied on albino rats. The drug was injected intraperitoneally in a dose of 25 mg/kg daily for 30 days. It was shown that reumycin had a comparatively low toxic effect on the peripheral circulatory system and hemopoiesis. It induced the signs of transitory anemia and did not suppress the regenerative capacity of the bone marrow. After the drug repeated use there was an increase in the platelet count and in the rate of blood coagulation. These signs vanished a month after the end of the treatment course.
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