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Autotransplantation of the Spleen Following Atraumatic Splenic Rupture Secondary to Infectious Mononucleosis: A Case Report.
Cureus
December 2024
Department of Upper Gastrointestinal and Hepatobiliary Surgery, Monash Health, Melbourne, AUS.
Atraumatic splenic rupture (ASR) is a rare and life-threatening condition that presents diagnostic difficulties due to its rarity and non-specific clinical symptoms. It often requires computed tomography (CT) imaging for accurate diagnosis and surgical planning. Splenectomy is the standard treatment for unstable patients, but autotransplantation of splenic tissue may reduce the lifelong risks of overwhelming post-splenectomy infections (OPSI) by preserving some immunological function.
View Article and Find Full Text PDFInfluence of Organ-Specific Extranodal Involvement on Survival Outcomes in Stage IV Diffuse Large B-Cell Lymphoma.
Cancer Med
January 2025
Lymphoma and Cell Therapy Research Center, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Background: The prognostic significance of extranodal sites in stage IV diffuse large B-cell lymphoma (DLBCL) remains uncertain, making it challenging to select appropriate treatment strategies for individual patients. In this study, we aimed to evaluate the influence of different extranodal sites on prognosis in young patients with stage IV DLBCL who achieved complete remission (CR) following initial chemo-immunotherapy and to explore the potential of autologous hematopoietic stem cell transplantation (ASCT) as a consolidation treatment for specific patient subgroups.
Methods: We retrospectively reviewed data from 119 patients with DLBCL aged < 60 years who achieved CR after chemo-immunotherapy between 2008 and 2020.
A rare case of wandering spleen with splenomegaly in a postpartum female patient: A case report and literature review.
Int J Surg Case Rep
December 2024
College of Surgeons of East, Central, and Southern Africa, 157 Olorien, Njiro Road ECSA-HC, P.O.Box 1009, Arusha, Tanzania.
Background: Wandering spleen or hypermobile spleen results from the elongation or maldevelopment of the spleen's suspensory ligaments. Few cases have been reported worldwide, making it a rare clinical entity. It usually affects children, although it also commonly affects female adults in the reproductive age range.
View Article and Find Full Text PDF[Clinical Characteristics and Prognosis of Patients with Primary Bone Marrow Lymphoma].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2024
Department of Hematology, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China.
Article Synopsis
- This study analyzes the characteristics and outcomes of 6 patients diagnosed with primary bone marrow lymphoma from 2011 to 2023 at Gansu Provincial People's Hospital.
- Patients had a median age of 61, with all presenting symptoms like fever and abnormal blood tests, but no signs of systemic lymphoma in other areas.
- The prognosis is generally poor, with a median overall survival of 5.5 months, though autologous stem cell transplantation could potentially enhance outcomes.
Autosplenectomy in systemic sclerosis.
Clin Rheumatol
October 2024
Department of Medicine, Division of Rheumatology, Queen's University, Kingston, ON, Canada.
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