The effects of propranolol, a noncardioselective beta-adrenergic blocking agent, and practolol, a cardioselective agent, on left ventricular function were compared in an awake dog model at an equiblocking dose range. Both agents produced modest depression of inotropic state at rest, and during volume and phenylephrine loading. No significant differences between the two agents were detected.
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http://dx.doi.org/10.1093/cvr/12.2.81 | DOI Listing |
Ann Endocrinol (Paris)
June 2021
Hypertension Unit, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris, 75015 Paris, France; Université de Paris, Paris, France; Université de Paris, PARCC, INSERM, Equipe Labellisée par la Ligue contre le Cancer, 75015 Paris, France. Electronic address:
Stress cardiomyopathy (SCM) is a syndrome characterized by transient regional systolic dysfunction of the left ventricle in the absence of angiographic evidence of coronaropathy. This abnormality is associated with high levels of catecholamines. Stress cardiomyopathy is also called Takotsubo (TS) cardiomyopathy.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
June 2020
Cleveland Clinic Foundation, Cleveland, Ohio.
Background: β-Adrenergic blockers (BBs) have been associated with increased risk for severe anaphylactic reaction (AR) from contrast media; however, this was shown with intravenous contrast media, before widespread use of low osmolar contrast media, angiotensin-converting enzyme-inhibitors (ACE-Is), and cardioselective BBs.
Objective: To assess the risk for AR during cardiac catheterization (CC) associated with BB or ACE-I exposure.
Methods: Patients who experienced adverse reactions during CC from January 2004 to December 2013 were identified; 1 to 2 matched controls were assigned for each case.
Heart Lung
November 2020
Department of Medicine, Division of Cardiology, Loyola University Medical Center, 2160 S First Ave, Suite 6232-6234, Maywood, 60153 IL, USA. Electronic address:
A 37-year-old woman with no past medical history presented with longstanding untreated hyperthyroidism and consequentially developed thyrotoxicosis-induced cardiomyopathy. Upon admission, she was noted with a heart rate of 172 beats per minute and an EKG consistent with supraventricular tachycardia which was unresponsive to adenosine. Shortly after the initiation of a non-cardioselective beta-blocker for the treatment of persistent tachycardia, she developed profound cardiogenic shock refractory to vasopressors and inotropes.
View Article and Find Full Text PDFAnn Pharmacother
December 2019
Ferris State University College of Pharmacy, Grand Rapids, MI, USA.
To review the rate of exacerbations relative to β-blocker use in patients with chronic obstructive pulmonary disease (COPD). A MEDLINE search (1953 to May 2019) was performed using the search terms , and . An EMBASE search was also performed using the search terms and (1970 to May 2019).
View Article and Find Full Text PDFIntroduction: Hyperkalemia secondary to beta-adrenergic receptor blockade occurs in 1-5% of patients and is likely to develop with non-cardio-selective beta-blockers.
Case Report: We have described hyperkalemia in a patient with angina pectoris receiving propranolol, clinically manifested as weakness, tightness behind the sternum and numbness in the limbs. Laboratory tests showed hyperkalemia (6.
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