Acute typhoid infection was induced in cocks of the New Hampshire breed at the age of 14 months within the period of intense productivity. Bacteriologically, there were in the viscera of cocks died of the acute infection organisms of Salmonella gallinarum--the isolates were from the heart, liver, spleen, and testis, while in the viscera of infected birds that were killed no such organisms were isolated. Histologically, there were necrobiotic and degenerative lesions in the epithelial cells of the seminiferous tubuli as well as disturbances in the process of spermiogenesis. The morphologic changes seen in the parenchymal organs were analogous with those that have been demonstrated so far. Cytologically, the semen of the infected cocks presented pathologically changes spermatozoa and anomalies of their head and tail; a large number of erythrocytes and leukocytes were also found.
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