After a short representation of the pathophysiology of incontinence following operation of anal atresia the possibilities of dietetic, medicamental, physiotherapeutic and psychotherapeutic therapy are discussed.
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Environ Toxicol Chem
January 2025
Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
A statistical procedure has been developed to derive a screening value from an observational study related to the developmental toxicity observed in loggerhead turtle (Caretta caretta) eggs exposed to long chain per- and polyfluoroalkyl substances (PFAS). A dataset of 41 nests in which the hatching rate was inversely correlated with the increase in the PFAS concentration in unhatched eggs was processed via a categorical regression approach. After outliers identification and removal, categorical regression analysis tested the relationships of the outcomes with the following parameters: perfluoro-nonanoic (PFNA), decanoic (PFDA), undecanoic (PFUdA), and dodecanoic (PFDoA) acids; perfluoroctansulfonate (PFOS); polychlorobiphenyls (PCBs) 28, 52, 101, 138, 153, 180; lead (Pb), total mercury (Hgtot), and cadmium (Cd); and other factors, such as "nest site," "clutch size," "incubation duration," and "nest minimum depth," as confounders/modifiers of the hatching rate.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Agriculture, Food and Nutrition, Weihenstephan-Triesdorf University of Applied Sciences, Weidenbach, Germany.
As global demand for meat continues to rise, alternative and sustainable methods of production are being explored. Cultivated meat (CM) is one such alternative that holds potential for sustainable production with less environmental impact. This study develops an approach to evaluate CM production based on agricultural feedstock.
View Article and Find Full Text PDFClin Oral Investig
January 2025
Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
Objective: To evaluate the possible additional clinical benefit from autologous platelet concentrate (APC) treatment adjunct to non-surgical periodontal therapy (NSPT).
Methods: Electronic (MEDLINE/Embase/Cochrane/MedNar/CORE) and hand searches were conducted. Following studies selection, evidence tables were formed, and meta-analyses were performed for the following outcomes: probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, and bleeding on probing (BoP) reduction.
Pediatr Nephrol
January 2025
Department of Pediatrics, University of California, San Diego, 3020 Children's Way MC 5173, San Diego, CA, 92123, USA.
Proliferative Glomerulonephritis with Monoclonal IgG Deposits (PGNMID) is a glomerular disease characterized by membranoproliferative and mesangioproliferative lesions, with granular capillary wall monoclonal IgG positivity and immunoglobulin light chain restriction. Most commonly a disease of older adults, we present the case of an 18-year-old patient who developed de novo PGNMID in a kidney allograft three years after kidney transplantation. There was minimal proteinuria and no serum paraproteinemia was detected, so the patient was managed conservatively.
View Article and Find Full Text PDFChem Sci
January 2025
Department of Chemical Physiology and Biochemistry, School of Medicine, Oregon Health & Science University 3181 SW Sam Jackson Park Road Portland Oregon 97239 USA
Mycobacterial hemerythrin-like proteins (HLPs) are important for the survival of pathogens in macrophages. Their molecular mechanisms of function remain poorly defined but recent studies point to their possible role in nitric oxide (NO) scavenging. Unlike any nonheme diiron protein studied so far, the diferric HLP from (-HLP) reacts with NO in a multistep fashion to consume four NO molecules per diiron center.
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