[Metabolism of chromatin lipids in rat liver and thymus].

The amount and the ratio of individual chromatin-bound phospholipids and cholesterol from rat thymus and liver, tissues that are essentially different in the rate of proliferation, have been estimated. In liver chromatin the amount of phospholipids is two times and cholesterol three times higher than in thymus chromatin (per mg of chromatin DNA). As indicated by 2-14C-acetate incorporation the intensity of chromatin lipid metabolism is substantially higher than that of lipids of the intact nuclei (particularly in thymus). The results obtained allow to conclude that chromatin lipids are spatially separated from other lipids of the nucleus.