The determination of spectrum of blood plasma fatty acids was performed in patients with purulent surgical infection. The surgical infection was shown to bring about changes in the content of free fatty acids (FFA) in blood plasma. In patients with sepsis undulatory changes in the content of FFA of blood plasma were typical. Sharp and stable decrease of FFA content was observed in patients with critical development of sepsis and lethal outcome. The increased content of FFA was established in patients with septic shock.
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