Two hundred patients with low-back pain syndrome were studied. The results of neurological examination were compared with those of radiculography in these cases. It was found that although herniation of the nucleus pulposus at the L4-5 level is twice as frequent as at the L5-S1 level, radicular signs were demonstrated in 69% caused by injury to the S1 root and in 57% by injury to the L5 root. In surgically treated cases agreement between the result of surgical exploration and the result of radiculography was demonstrated in 99.7% of cases.
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AJNR Am J Neuroradiol
January 2025
University of Utah Department of Radiology and Imaging Sciences (D.A., T.A.H., L.M.S., M.E.P.), Salt Lake City, Utah.
CT-guided C1-C2 facet joint injections are a valuable tool for managing cervicogenic headaches caused by degenerative and inflammatory conditions of the atlantoaxial joint. This video article presents the procedural technique for a CT-guided C1-C2 facet joint injection in a patient with left-sided cervicogenic headache. Despite concerns regarding potential complications such as vascular injury to the vertebral artery and nerve injury to the C2 dorsal root ganglion, careful anatomic planning and imaging guidance allows safe and effective treatment.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
School of Nuclear Science and Technology, Lanzhou University, Gansu Lanzhou 730000, China; School of Stomatology, Lanzhou University, Gansu Lanzhou 730000, China; Gansu Key Laboratory of Dental and Maxillofacial Reconstruction and Bio-intelligent Manufacturing, School of Stomatology, Lanzhou University, Gansu Lanzhou 730000, China. Electronic address:
Background: Total glucosides of paeony (TGP), derived from the dried root of Paeonia, is a popular treatment for immune diseases. Radiation induced brain injury (RBI) is a common side effect of brain radiation therapy, but the efficacy of TGP in treating RBI remains uncertain.
Purpose: To evaluate the protective effects of TGP against RBI and elucidate its underlying mechanisms using pharmacological network analysis, molecular docking, and experimental validation.
J Int Med Res
January 2025
Department of Emergency Medicine, The Second Hospital of Lanzhou University, Lanzhou, Gansu, PR China.
Lumbar burst fractures account for 21% to 58% of all thoracolumbar fractures. L5 lumbar burst fractures are rare, comprising 1.2% of spinal burst fractures.
View Article and Find Full Text PDFSubst Abuse Rehabil
January 2025
Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University Wilberforce Island Bayelsa State, Amassoma, Nigeria.
Background: Datura metel is reported to induce hallucinations and mental disorders.
Objective: This study investigates the neurotoxic effects of stramonium hydroethanolic root extract on the hippocampus and cerebral cortex of adult rats using biochemical, histological and immunohistochemical techniques.
Methodology: Twenty five adult rats were assigned to 5 groups (n = 5 each).
J Ethnopharmacol
January 2025
Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, P.R. China. Electronic address:
Ethnopharmacological Relevance: The roots of Oxybaphus himalaicus Edgew. is a traditional Tibetan herbal medicine with kidney reinforcing and tonifying effects, which is commonly applied to treat nephritis. Boeravinone C has been identified as one of the primary constituents of O.
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