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Evaluating the Statistical Fragility of Comparative Studies on Autografts for Pediatric ACL Reconstruction.
Orthop J Sports Med
February 2025
Department of Orthopaedic Surgery, University of California-San Francisco, San Francisco, California, USA.
Background: The literature presents conflicting findings regarding outcomes after pediatric anterior cruciate ligament reconstruction (ACLR) with various autograft options, reflecting a lack of consensus on the standard of practice. Fragility analyses may assist in evaluating the statistical robustness of these studies.
Purpose: To evaluate the statistical fragility of comparative studies in pediatric ACLR through the fragility index (FI) and fragility quotient (FQ), as well as qualitative factors such as outcome type, outcome significance, and patients lost to follow-up.
New insights in the systematics of the Hemiuroidea (Digenea: Hemiurata) based on the integrative taxonomy approach.
Syst Parasitol
January 2025
Pacific branch of the Federal State Budget Scientific Institution "Russian Federal Research Institute of Fisheries and Oceanography", 4 Alley Shevchenko, Vladivostok, Russian Federation, 690091.
Opistholecithum sandugaense n. g. n.
View Article and Find Full Text PDFNovel Copper(II) Coordination Compounds Containing Pyridine Derivatives of -Methoxyphenyl-Thiosemicarbazones with Selective Anticancer Activity.
Molecules
December 2024
Laboratory of Advanced Materials in Biopharmaceutics and Technics, Institute of Chemistry, Moldova State University, MD-2009 Chisinau, Moldova.
Ten coordination compounds, [Cu(L)Cl] (), [Cu(L)NO] (), [Cu(L)Cl] (C3), [Cu(L)NO] (), [Cu(L)Cl] (), [Cu(L)NO] (), [Cu(L)NO] (), [Cu(L)Cl] (), [Cu(L)Cl] (), and [Cu(L)NO] (), containing pyridine derivatives of -methoxyphenyl-thiosemicarbazones were synthesized and characterized. The molecular structure of four compounds was investigated using single crystal X-ray diffraction. Spectral analysis techniques such as FT-IR, H NMR, C NMR, elemental analysis, and molar conductivity were used for all the synthesized compounds.
View Article and Find Full Text PDFImproving Septicemia Diagnostics: A Comparative Analysis of Direct and Post-Culture MALDI-TOF MS Methods for Bacterial Identification.
Tunis Med
December 2024
Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
Article Synopsis
- Bloodstream infections need quick bacterial identification for effective treatment, with traditional methods being slow.
- The study compared direct identification using MALDI-TOF MS with the post-culture method, finding that while direct identification had a lower success rate (64.8%), it provided results in under an hour.
- Despite its limitations, the direct method could significantly enhance diagnosis speed, making it a potentially valuable tool in conjunction with established methods.
Medial meniscus ramp tears: State of the art.
J ISAKOS
February 2025
Twin Cities Orthopedics, Edina, MN, USA. Electronic address:
Medial meniscus ramp tears are tears of the posteromedial capsule or peripheral rim of the posteromedial meniscus that frequently occur with anterior cruciate ligament (ACL) tears. The incidence and prevalence of medial meniscus ramp tears has been increasing in the recent literature due to the increased understanding of the anatomy and diagnosis of these tears. When a patient presents with an ACL tear, a medial meniscus ramp tear should be suspected if the patient has a grade 3+ Lachman or pivot-shift exam, a vertical line of increased signal intensity in the posterior capsule or peripheral meniscus on magnetic resonance imaging (MRI), or posteromedial tibial plateau bone bruising on MRI.
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