Data concerning two whole brothers with familial cardiomyopathy diagnosed during life are discussed. The disease was manifetsed in the brothers by similar clinical and instrumental symptoms, namely, congestive circulatory insufficiency, marked hypertrophy mainly of the left parts of the heart, and pronounced cardiomegalia. The diagnosis was confirmed by intravital myocardial puncture biopsy which yielded evidence in favour of clear-cut predominance of processes of hypertrophy with no manifestations of an active inflammatory reaction.
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