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A Review on Curability of Cancers: More Efforts for Novel Therapeutic Options Are Needed.
Cancers (Basel)
November 2019
KU Leuven, Campus Gasthuisberg, Faculty of Medicine, 3000 Leuven, Belgium.
Cancer remains a major cause of death globally. Given its relapsing and fatal features, curing cancer seems to be something hardly possible for the majority of patients. In view of the development in cancer therapies, this article summarizes currently available cancer therapeutics and cure potential by cancer type and stage at diagnosis, based on literature and database reviews.
View Article and Find Full Text PDFBasic studies on a labeled anti-mucin antibody detectable by infrared-fluorescence endoscopy.
J Gastroenterol
November 2002
Second Department of Internal Medicine, University of Tokushima School of Medicine, Japan.
Background: We developed a fluorescent dye, indocyanine green (ICG)-sulfo-OSu, which was excited by infrared rays and conjugated to various antibodies. We attempted to clarify the staining patterns of antisulfomucin and anti-MUC1 antibodies in gastrointestinal cancer. We then evaluated the potential of the dye as a fluorescent label for antibodies specific to cancer, to be used as a diagnostic method for microcancer, with infrared fluorescence endoscopy.
View Article and Find Full Text PDFVital immunohistochemical staining for a novel method of diagnosing micro-cancer. Examination of immunohistochemical staining of non-fixed fresh tissue.
J Med Invest
August 1999
Second Department of Internal Medicine, University of Tokushima School of Medicine, Japan.
It becomes possible to establish a novel diagnostic method for micro-cancer by modulating the signals from the lesion, if lesions can be labeled with substances which can be detected by video endoscopy. The authors have already succeeded in synthesizing indocyanine green (ICG) derivatives for a fluorescent labeling substance which emits near-infrared rays. Before the antibodies labeled by these substances can be used, it is necessary to establish a method of vital immunohistochemical staining.
View Article and Find Full Text PDF[Clinicopathological study of esophageal cancer in the early stage and its later development].
Gan To Kagaku Ryoho
March 1985
Ninety-five specimens taken from 82 cases of superficial esophageal cancer limited within the submucosal layer were studied to clarify the developmental changes of early esophageal cancer. Esophageal epithelium was also open to cancerous or dysplastic changes. Cancers limited to the mucosal layer were grossly classified as follows.
View Article and Find Full Text PDF[Esophageal microcancers (8 subclinical and subradiological cancers)].
J Fr Otorhinolaryngol Audiophonol Chir Maxillofac
March 1980
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