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Vibrio parahaemolyticus is an important foodborne pathogen, of which the 03:K6 serotype caused many outbreaks in different countries since 1996. Based on the 10 years data (1992-2001) from China, gastroenteritis caused by Vibrio parahaemolyticus accounted for 31.1% of foodborne disease outbreaks that were resulted from microorganisms.
View Article and Find Full Text PDF[Type III secretion system of Vibrio parahaemolyticus--a review].
Wei Sheng Wu Xue Bao
July 2009
Zhejiang Key Laboratory of Preventive Veterinary Medicine, Zhejiang University, Hangzhou 310029, China.
Vibrio parahaemolyticus is a halophilic gram-negative bacterium that causes food borne acute gastroenteritis in human being or certain diseases in aquatic species. In addition to thermostable direct hemolysin (tdh) and tdh-related hemolysin (trh), two sets of type III secretion systems (T3SS) were recently found to be associated closely with virulence. T3SS1 located on chromosome 1 is involved in cytotoxicity to host cells and orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and eventual cell lysis.
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