Authors dealing with the dentin tissue arrange the structurally various kinds of it into primary, secondary and tertiary dentin agreeing fully with the classification of Kuttler. Varieties of the tertiary dentin are shown. Explanation is given for the forming of tertiary dentin at the floor of the pulpchamber of molars.
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Int J Mol Sci
December 2024
Institute of Physiology, University of Würzburg, 97070 Würzburg, Germany.
Nitric oxide-sensitive guanylyl cyclase (NO-GC) is a heterodimeric enzyme with an α- and a β-subunit. In its active form as an αβ-heterodimer, NO-GC produces cyclic guanosine-3',5'-monophophate (cGMP) to regulate vasodilation and proliferation of vascular smooth muscle cells (VSMCs). In contrast to VSMCs, only a few studies reported on the expression of the NO-GC αβ-heterodimer in human pericytes.
View Article and Find Full Text PDFClin Oral Investig
January 2025
Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Objectives: The aim of this systematic review was to assess the effect of DM (Type 1 and Type 2 Diabetes) and hyperglycaemia on the physical and mechanical properties of dentine which is critical for successful endodontic treatment.
Method: An electronic search of the following databases: PubMed, MEDLINE, Web of Science and the grey literature was performed up until July 2024. In vitro and in vivo studies on the effect of DM or hyperglycaemia on the mechanical and physical properties of dentine were included.
bioRxiv
December 2024
Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago 60612, IL, USA.
Dental caries is one of the most common health issues worldwide arising from the complex interactions of bacteria. In response to harmful stimuli, desirable outcome for the tooth is the formation of tertiary dentin, a protective reparative process that generates new hard tissue. This reparative dentinogenesis is associated with significant inflammation, which triggers the recruitment and differentiation of dental pulp stem cells (DPSCs).
View Article and Find Full Text PDFJ Dent
February 2025
Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal do Rio de Janeiro (UFRJ), Rodolpho Paulo Rocco, 325, Rio de Janeiro, RJ 21941-617, Brazil. Electronic address:
Objectives: To identify and map the literature on the current state of pH-triggered strategies for resin-based materials used in direct restorative dentistry, focusing on innovative compounds, their incorporation and evaluation methods, and the main outcomes.
Data And Sources: Through a search across PubMed, Scopus, Embase, Web of Science, LILACS, Cochrane Library databases, and Google Scholar, this review identified studies pertinent to pH-responsive dental materials, excluding resin-modified glass ionomer cements.
Study Selection: From the 981 records identified, 19 in vitro studies were included, concentrating on resin-based composite resins (50 %), dentin adhesives (25 %), and sealants (25 %).
Restor Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, TPCT's Terna Dental College, Maharashtra, India.
Unlabelled: This review aimed to evaluate and compare the biological response (biocompatibility and cytotoxicity) of resin modified glass ionomer cement (RMGIC) in contrast to conventional glass ionomer cement (GIC) on human cells. Articles reporting parallel and split-mouth clinical trials, randomized controlled trials, non-randomized controlled trials, prospective studies, and studies on human permanent teeth that assessed the biological response of GIC and RMGIC were included. The following electronic bibliographic databases were searched using the keywords: MEDLINE/PubMed, EBSCO, Cochrane Central Register of Controlled Trials, and Google Scholar.
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