The reaction of the connective tissue component of the rat left ventricular myocardium to hypertrophy induced by ventral aorta coarctation in the subdiaphragmatic part was studied by electron microscopy with the use of morphometric analysis. The animals were sacrificed 1, 5 and 10 days after the operation. It the heart of intact animals, the relative amount of the connective tissue was equal to 10.2%. Of this number, 2% were cellular elements, 0.2 and 8% were fibrous and amorphous parts of the intermediate tissue, respectively. In the emergency stage of hypertrophy there was an augmentation of the total amount of the connective tissue, the ratio of its diverse components varied with time. Moreover, an activation of the synthetic processes was recorded in the cells of the fibroblastic type.
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