Four cases of an unusual skin eruption related to mandibular block injection are presented. The authors suggest an immunologic basis for the reaction, probably to the methylparaben preseravtive, and discuss a possible pathogenic mechanism. The medical-dental literature concerning untoward reactions to lidocaine is reviewed; particular attention is given alleged allergic reactions.

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http://dx.doi.org/10.1016/0030-4220(80)90028-6DOI Listing

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