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Novel index for the evaluation of wound healing following erupted tooth extraction.
Minerva Dent Oral Sci
January 2025
Department of Surgical, Medical, Molecular and Critical Area Pathology, University Hospital of Pisa, University of Pisa, Pisa, Italy.
Background: Understanding healing of the alveolar process is crucial for immediate implant, alveolar ridge preservation and guided bone regeneration procedures, and to evaluate it several different scales have been proposed; however, all have different characteristics and seem to miss a standardization allowing for an objective and dichotomous evaluation of the different aspects of wound healing. The objective of the present study is to propose and apply, in real clinical scenarios, a novel index for the objective evaluation of wound healing following erupted tooth extraction.
Methods: Healthy patients in need of a single tooth extraction were enrolled and re-examined at 7, 14 and 21 days after the extraction using the novel index proposed.
Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote Alveolar Wound Healing.
Pharmaceutics
January 2025
Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy.
Article Synopsis
- Resveratrol (RSV) can aid healing after tooth extraction by reducing inflammation, but its effectiveness is limited by poor solubility.
- Researchers developed a nanocomposite by combining RSV with lipid nanoparticles in a hydrophilic matrix to improve its delivery and enhance patient recovery.
- The optimal PEG-based nanocomposites, when combined with hydroxyapatite, were found to work well as pharmaceutical powders for creating mini-tablets that can effectively release RSV into buccal tissue, promoting better healing in the surgical site.
Effect of Bacterial Nanocellulose with Chemisorbed Antiseptics on Alveolar Bone Repair in Rats Undergoing Bisphosphonate Therapy.
Pharmaceutics
December 2024
Post-Graduate Program in Dentistry, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre 90619-900, RS, Brazil.
: This work investigated the effect of bacterial nanocellulose (BNC) alone or with chemisorbed chlorhexidine or povidone-iodine on post-tooth extraction repair in rats undergoing bisphosphonate therapy. : Forty Wistar rats were treated with zoledronic acid, subjected to tooth extractions and allocated into groups according to the material inserted in the post-extraction socket: (1) BNC ( = 10); (2) BNC/Iodine ( = 10); (3) BNC/Chlorhex ( = 10); (4) Control ( = 10). Maxillae were dissected and macro- and microscopically analyzed.
View Article and Find Full Text PDFAdvancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review.
Diagnostics (Basel)
January 2025
Department of Periodontology, Faculty of Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
: Tooth extraction induces significant alveolar ridge dimensional changes and soft tissue modifications, often leading to challenges in implant placement or conventional prosthetic rehabilitation. Alveolar Ridge Preservation (ARP) strategies aim to mitigate post-extraction resorption of the alveolar ridge, enhancing both the quality and quantity of bone and soft tissue during healing. Hyaluronic acid (HYA) has emerged as a promising biological agent for ARP due to its osteoinductive, antimicrobial, and anti-inflammatory properties.
View Article and Find Full Text PDFSocket Sealing Using Free Gingival Grafts: A Randomized Controlled Trial.
Dent J (Basel)
January 2025
Department of Oral Surgery, Faculty of Dental Medicine, Medical University of Varna, 9002 Varna, Bulgaria.
Post-extraction ridge resorption is an inevitable phenomenon that cannot be eliminated but is significantly reduced using additional surgical techniques known as socket preservation. They aim to create favorable conditions for implant placement and prosthetic restoration. This study aims to assess the effect of socket sealing (SS) with free gingival grafts on the vertical resorption of socket walls at the premolar and molar regions over 3 months.
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