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Extraversion and the Brain: A Coordinate-Based Meta-Analysis of Functional Brain Imaging Studies on Positive Affect.
J Evid Based Med
January 2025
School of Teacher Education, Dali University, Dali, China.
Objective: Extraversion is a fundamental personality dimension that contributes to an individual's overall health and well-being. Many studies have examined the neural bases of extraversion but these results are inconsistent. This study adopted a meta-analysis approach to examine the brain activity correlates of extraversion by incorporating functional neuroimaging studies in the context of positive affect/emotional stimuli.
View Article and Find Full Text PDFCross-cultural validation of plasma p-tau217 and p-tau181 as precision biomarkers for amyloid PET positivity: An East Asian study in Taiwan and Korea.
Alzheimers Dement
January 2025
Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Introduction: Plasma phosphorylated tau (p-tau) biomarkers have improved Alzheimer's disease (AD) diagnosis, but data from diverse Asian populations are limited. This study evaluated plasma p-tau217 and p-tau181 levels in Korean and Taiwanese populations.
Methods: All participants (n = 270) underwent amyloid positron emission tomography (PET) and blood tests.
Anxiety, depression, and their association with unintentional injury risk among older adult populations in Guangxi, China: a cross-sectional study.
Front Public Health
January 2025
Department of Health Care Management, School of Information and Management, Guangxi Medical University, Nanning, Guangxi, China.
Background: The aging population presents a significant public health challenge, particularly concerning mental health and injury prevention. Anxiety and depression are common among the older adult, affecting their quality of life and increasing the risk of unintentional injuries (UI). This study aims to explore the association between anxiety and depression and UI risk among the older adult in Guangxi, China, using data from the 2023 National Health Service Survey.
View Article and Find Full Text PDFCausal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.
Front Endocrinol (Lausanne)
January 2025
School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Objective: Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. While multiple studies have indicated changes in the expression of specific matrix metalloproteinases (MMPs) in patients with DN, and basic research has reported the impact of MMPs on DN, there is a lack of systematic research and the causal relationship remains unclear. The objective of this research is to investigate the casual relationship between MMPs and DN through two-sample Mendelian randomization (MR).
View Article and Find Full Text PDFAssociations between serum total bilirubin and overactive bladder from the National Health and Nutrition Examination Survey.
Front Endocrinol (Lausanne)
January 2025
Department of Urology, Affiliated Yancheng Hospital, School of Medicine, Southeast University, Yancheng, Jiangsu, China.
Background: The relationship between serum total bilirubin (STB) concentrations and the risk of overactive bladder (OAB) remains uncertain. This study aims to explore the potential connection between STB and OAB.
Method: We utilized data from the National Health and Nutrition Examination Survey (NHANES) database for the years 2001-2020.
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