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How do tumours outside the gastrointestinal tract respond to dietary fibre supplementation?
BMJ Oncol
November 2023
Rowett Institute, University of Aberdeen, Aberdeen, UK.
Cancer remains one of the leading causes of death worldwide, despite advances in treatments such as surgery, chemotherapy, radiotherapy and immunotherapy. The role of the gut microbiota in human health and disease, particularly in relation to cancer incidence and treatment response, has gained increasing attention. Emerging evidence suggests that dietary fibre, including prebiotics, can modulate the gut microbiota and influence antitumour effects.
View Article and Find Full Text PDFUse of immunosuppression and subsequent cancer incidence: cohort study.
BMJ Oncol
August 2023
Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Objective: Evaluate the association between cancer incidence and immunosuppressive treatment in patients with ocular inflammatory disease (OID).
Methods And Analysis: We performed a retrospective cohort study of patients from 10 US OID subspecialty practices. Patients with non-infectious OID were included; HIV-infected patients were excluded.
A comparison of the persuasiveness of human and ChatGPT generated pro-vaccine messages for HPV.
Front Public Health
January 2025
CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Introduction: Public health messaging is crucial for promoting beneficial health outcomes, and the latest advancements in artificial intelligence offer new opportunities in this field. This study aimed to evaluate the effectiveness of ChatGPT-4 in generating pro-vaccine messages on different topics for Human Papillomavirus (HPV) vaccination.
Methods: In this study ( = 60), we examined the persuasive effect of pro-vaccine messages generated by GPT-4 and humans, which were constructed based on 17 factors impacting HPV vaccination.
Management of Idiopathic Granulomatous Mastitis: Effectiveness of a Steroid-Free Regimen Using -A Single-Institution Experience.
Breast J
January 2025
Department of Surgical Oncology, Breast Services, Tata Memorial Centre and Homi Bhabha National Institute, Mumbai, India.
Idiopathic granulomatous mastitis (IGM) is a benign, chronic inflammatory disease with no effective treatment and high relapse rate. The pathophysiology is poorly understood. Tinosporin, an immunomodulator obtained from , is known to be useful in treating immune-mediated diseases.
View Article and Find Full Text PDFUnravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.
Front Immunol
January 2025
School of Interdisciplinary Engineering and Sciences (SINES), Department of Sciences, National University of Sciences and Technology (NUST), Islamabad, Pakistan.
The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been associated with several complications.
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