The description of female, male and 4th stage larva of a new species of mosquito, Aedes (Stegomyia) sibiricus, from Siberia and Far East of the USSR is given. This species belonging to the albopictus subgroup of the scutellaris group of species was formerly confused with A. (S.) galloisi Yam. The geographical distribution of A. sibiricus is related to the south of the East taiga and Okhotsk districts of the Euro-Siberian province of the Circumboreal subregion of the Palearctic, while A. galloisi is spread in the Chinese-Himalayan subregion and has been recorded in the Soviet Union from the Sakhalin Island only (the geographical distribution of this species is shown on a map).
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Appl Environ Microbiol
January 2025
Symbiosis Technologies for Insect Control (SymbioTIC), Plateforme de Recherche CYROI, Ste Clotilde, France.
The bacterium is increasingly studied for its potential use in controlling insect vectors or pests due to its ability to induce Cytoplasmic Incompatibility (CI). CI can be exploited by establishing an opportunistic infection in a targeted insect species through trans-infection and then releasing the infected males into the environment as sterilizing agents. Several host life history traits (LHT) have been reported to be negatively affected by artificial infection.
View Article and Find Full Text PDFFront Immunol
January 2025
Infectious Disease Research Department, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University of Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Due to their widespread geographic distribution and frequent outbreaks, mosquito-borne flaviviruses, such as DENV (DENV), Zika virus (ZIKV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), and West Nile virus (WNV), are considered significant global public health threats and contribute to dramatic socioeconomic imbalances worldwide. The global prevalence of these viruses is largely driven by extensive international travels and ecological disruptions that create favorable conditions for the breeding of and species, the mosquito vectors responsible for the spread of these pathogens. Currently, vaccines are available for only DENV, YFV, and JEV, but these face several challenges, including safety concerns, lengthy production processes, and logistical difficulties in distribution, especially in resource-limited regions, highlighting the urgent need for innovative vaccine approaches.
View Article and Find Full Text PDFJ Med Entomol
January 2025
Center for Vector Biology & Zoonotic Diseases, Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT, USA.
Filarial nematodes are parasitic roundworms transmitted by mosquitoes that can cause morbidity and mortality for their human and animal hosts. The filariae community, specifically infection prevalence of heartworm, Dirofilaria immitis (Filarioidea: Onchocercidae) (Leidy), and its primary mosquito vector species, has not been described in Connecticut since 1977. In light of the recent invasion and establishment of an important filariasis vector, Aedes albopictus (Diptera: Culicidae) (Skuse), we used molecular-based sequencing methods to identify filarial species infecting field-caught mosquitoes in Connecticut, United States.
View Article and Find Full Text PDFCommun Biol
January 2025
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, 350401, Taiwan.
Metabolic and neurological disorders commonly display dysfunctional branched-chain amino acid (BCAA) metabolism, though it is poorly understood how this leads to neurological damage. We investigated this by generating Drosophila mutants lacking BCAA-catabolic activity, resulting in elevated BCAA levels and neurological dysfunction, mimicking disease-relevant symptoms. Our findings reveal a reduction in neuronal AMP-activated protein kinase (AMPK) activity, which disrupts autophagy in mutant brain tissues, linking BCAA imbalance to brain dysfunction.
View Article and Find Full Text PDFGiven recent outbreaks of Oropouche virus in Latin America and >100 confirmed travel-associated cases in the United States, we evaluated the competence of US vectors, including Aedes albopictus, Culex quinquefasciatus, Culex pipiens, and Anopheles quadrimaculatus mosquitoes. Results with historic and recent isolates suggest transmission potential for those species is low.
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