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Antimicrobial efficacy of alternative root canal disinfection strategies: An evaluation on multiple working models.
Biomed Pharmacother
January 2025
Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (FOB - USP), Bauru, São Paulo, Brazil. Electronic address:
Researching disinfection strategies is pivotal because effectively eliminating bacteria and their byproducts during root canal treatment (RCT) remains a challenge. This study investigated the antimicrobial efficacy of natural antimicrobial compounds, propolis (PRO) and copaiba oil-resin (COR), compared to conventional agents in Endodontics. Antimicrobials were tested against endodontic pathogens via macrodilution with standardized inoculums to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC).
View Article and Find Full Text PDFBiomimetic Confined Assembly of Plasmonic CuS from Electronic Waste for Rapid Photothermal Disinfection.
ACS Nano
January 2025
State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China.
Photothermal disinfection (PTD) offers promising potential for water purification due to its sustainable and broad-spectrum bactericidal properties, although it is hindered by slow charge separation in photosensitizers. Herein, we present a plasma-mediated PTD technique utilizing an efficient localized heating effect induced by incident light at specific wavelengths for rapid bacterial inactivation. A metallic CuS photosensitizer, derived from electronic waste through a biomimetic transmembrane confined-assembled strategy, facilitates collective and coherent oscillation of free electrons around Cu atoms in the near-infrared range.
View Article and Find Full Text PDFLong-lasting and controlled-release borate as a biocide against microbial breeding in a recirculating cooling water system.
Sci Total Environ
January 2025
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China; The Key Laboratory of Water and Sediment Sciences, Ministry of Education, School of Environment, Beijing Normal University, Beijing 100875, China.
Based on the potential bactericidal properties of borate, we synthesized controlled-release borate (CRB) as a novel biocide to inhibit microbial proliferation in a recirculating cooling water system (RCS). In this study, toxicity experiments of CRB were conducted on the dominant bacteria and algae isolated from an actual RCS. The effects of CRB on biocidal performance and genotoxicity were evaluated in a simulated RCS.
View Article and Find Full Text PDFNosocomial , , , and : Sensitivity to Chlorhexidine-Based Biocides and Prevalence of Efflux Pump Genes.
Int J Mol Sci
January 2025
Department of Microbiology, Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
The widespread use of disinfectants and antiseptics has led to the emergence of nosocomial pathogens that are less sensitive to these agents, which in combination with multidrug resistance (MDR) can pose a significant epidemiologic risk. We investigated the susceptibility of nosocomial , , , and to a 0.05% chlorhexidine (CHX) solution and a biocidal S7 composite solution based on CHX (0.
View Article and Find Full Text PDFEffect of Antimicrobial Wipes on Hospital-Associated Bacterial and Fungal Strains.
Infect Chemother
December 2024
Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea Seoul, Korea.
Background: Healthcare-associated infections (HAI) caused by multidrug-resistant organisms have emerged as a significant global issue, posing substantial challenges to healthcare systems. Low- and intermediate-level disinfectants are extensively utilized for cleaning and disinfecting surfaces in hospitals to mitigate environmental transmission of HAI. Therefore, the need for more effective and environmentally safe disinfectants is increasing.
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