A combined dialyzer-oxygenator system that removes CO2 extracorporeally is described. This system was devised to support the exchange of gases through the natural lungs and to diminish the rate of extracorporeal blood flow during prolonged gas exchange. The total CO2 removed was 20 ml/m2-min at an inlet PCO2 of 60 mm Hg. This removal was independent of the blood flow rate in the range of 100-300 ml/min. In studies in vitro, disturbances in blood electrolytes were compensated for by the selection of the appropriate composition of the dialysate fluid.
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