Syntheses of the peptides with sequences postulated for active and inactive isomer of edeine D were carried out. The peptides obtained were identical with natural product in regard to chromatographic and electrophoretic properties. Biological data for synthesized compounds confirmed that in active and inactive isomer isoserine is linked with the alpha- or beta-amino group of alpha, beta-diaminopropionic acid, respectively.
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http://dx.doi.org/10.7164/antibiotics.36.1001 | DOI Listing |
Front Sports Act Living
January 2025
Department of Public Health and Sport Sciences, University of Inland Norway, Elverum, Norway.
Introduction: Physical inactivity is a global health challenge, exacerbated by increased screen time and sedentary behaviors. Enhancing physical activity levels at schools offers a promising approach to promote lifelong healthy habits.
Methods: This protocol paper outlines the MOVE12 pilot study, a 12-week intervention study designed to increase physical activity among Norwegian upper secondary school students through 6-7-min daily MOVE-breaks integrated into lessons.
Front Public Health
January 2025
Department of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China.
Introduction: Osteoarthritis (OA) is a prevalent and debilitating disorder that affects the joints and has a complex array of causes. While sedentary behavior (SB) and physical activity (PA) have been implicated in OA risk, the relationship between these factors and OA development remains unclear. This study investigates the correlation and potential causality between SB, PA, and OA using both cross-sectional and Mendelian randomization (MR) analysis.
View Article and Find Full Text PDFOpen Res Eur
January 2025
Neuromotor Behavior and Exercise, University of Münster, Münster, Germany.
Background And Objectives: This is a protocol for a living systematic review and meta-analysis.This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.
View Article and Find Full Text PDFBMC Womens Health
January 2025
Department of Physiotherapy, University of Valencia, Valencia, 46010, Spain.
Background: This study aimed to investigate the relationship of psychological empowerment and enjoyment of physical activity with changes in physical activity levels, sleep quality, and muscular endurance following a high-intensity interval training (HIIT) program in physically inactive young women.
Methods: A total of 61 physically inactive young women (age: 20.1 ± 2.
BMC Geriatr
January 2025
Department of Health Economics, School of Public Health, Fudan University, 130 Dong'an Road, Shanghai, 200032, China.
Background: Multimorbidity has emerged as a significant challenge for healthcare systems globally. This study aims to examine the associations between key determinants of lifestyle behavior and various multimorbidity patterns.
Methods: In a cross-sectional sample of older adults (aged 60-79) from the Fifth National Physical Fitness Surveillance in Shanghai, latent class analysis (LCA) was used to identify multimorbidity patterns among 9 chronic diseases.
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