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Article Synopsis
  • Listeriosis is a serious public health concern due to its high death rate, prompting this study to explore its characteristics in Madagascar, where it's a reported disease.
  • The research zeroes in on a deadly case of meningeal listeriosis in a 12-year-old, discovering a unique genomic type of the bacteria with specific virulence and drug resistance traits.
  • This study marks the first genomic profiling of Listeria in Madagascar, underscoring the need for continuous surveillance to improve prevention and control efforts in the area.
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is a relatively uncommon cause of foodborne infection in the general population. Most cases of Listeriosis occur among newborns, pregnant women, the elderly and those with impairment of cellular immunity. Neonatal Listeria meningitis is rare.

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Article Synopsis
  • A rare gram-positive bacillus, an intracellular pathogen, can cause severe complications in pregnancy, leading to conditions like neonatal meningitis, as seen in two documented cases.
  • The first case involved a 7-day-old baby with high fever and feeding refusal, diagnosed with meningitis due to a CAMP-negative strain, requiring intensive treatment and mechanical ventilation before improving on appropriate antibiotics.
  • The second case involved an 11-day-old low birth weight infant who displayed symptoms suggestive of sepsis, prompting immediate empirical antibiotic administration and further investigation.
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BACKGROUND Bacterial meningitis is a serious and life-threatening condition that requires prompt diagnosis and treatment. This retrospective study aimed to identify causes, presentation, and predictive factors for outcomes of community-acquired bacterial meningitis in 86 adults in Vilnius, Lithuania between 2018 and 2021. MATERIAL AND METHODS We performed a retrospective study of demographic, clinical, and laboratory records of 86 adult patients admitted to Vilnius University Hospital Santaros Clinics with a diagnosis of acute bacterial meningitis during the period of 2018-2021.

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Case Report: A case of disseminated cutaneous listeriosis following appendicitis from Lao PDR.

Wellcome Open Res

May 2024

Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.

Background: is a food-borne pathogen that is a rare cause of bacteraemia and meningitis in immunosuppressed patients, and carries a high mortality rate. Cutaneous manifestations of listeriosis are rare, and are usually associated with direct inoculation of the skin.

Case: A 41-year-old woman who initially presented to a hospital in Laos with appendicitis was diagnosed with disseminated listeriosis with cutaneous involvement.

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