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BACKGROUND The configuration of the hepatic arteries is known to vary substantially between individuals. Here, we report a rare retroperitoneal configuration of an accessory hepatic artery existing alongside a left and right hepatic artery branching from the proper hepatic artery. During routine dissection, we discovered an anomalous configuration of the hepatic arteries that does not fit the commonly used categorizations for abnormal hepatic vasculature.

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Pathologic diagnosis and molecular features of gastrointestinal stromal tumors: a mini-review.

Front Oncol

November 2024

Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Article Synopsis
  • * About 80% of GISTs have mutations in KIT or PDGFRA that affect how they behave and respond to treatment; a special type called SDH-deficient GISTs is linked to certain genetic syndromes and presents different challenges.
  • * The primary treatment involves surgery and the drug imatinib for advanced cases, but resistance to treatment is a major issue, particularly in kids and wildtype GISTs, highlighting the need for better therapies and personalized treatment approaches.
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Pancreaticobiliary maljunction (PBM) is a congenital anomaly where the pancreatic and bile ducts join outside the duodenal wall, resulting in formation of an elongated common channel. In normal physiology, the sphincter of Oddi regulates the junction between the pancreatic and bile ducts. Individuals with PBM lack this regulatory mechanism resulting in reflux of pancreatic juices into the biliary tract.

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Mediastinal emphysema in the context of perforated gastric ulcer.

World J Clin Cases

May 2024

Department of Emergency Medicine, Wythenshawe Hospital, Manchester M23 9LT, United Kingdom.

Article Synopsis
  • The primary causes of mediastinal emphysema/pneumomediastinum include oesophageal perforation, lung issues, or complications from head and neck surgery.
  • Differentiating these causes can be effectively done using Computed Tomographic Imaging of the thorax and abdomen, utilizing oral and intravenous contrast in a triple phase approach.
  • Oesophageal perforation, known as Boerhaave syndrome, may present with Mackler's triad (severe chest pain, pneumomediastinum, mediastinitis) in about 50% of patients, while lung pathologies might present with pneumothorax and pleural effusion.
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Bouveret's syndrome is an uncommon cause of gastrointestinal obstruction. It's a result of the passage of a gallstone through a fistula connecting the gallbladder with the duodenum or stomach. The diagnosis is challenging due to its atypical clinical manifestations.

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