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Exploring Disparities in Gill Physiological Responses to NaHCO-Induced Habitat Stress in Triploid and Diploid Crucian Carp (): A Comprehensive Investigation Through Multi-Omics and Biochemical Analyses.
Metabolites
December 2024
Laboratory of Quality & Safety Risk Assessment for Aquatic Products (Harbin), Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Ministry of Agriculture and Rural Areas, Harbin 150070, China.
: Owing to the progressive rise in saline waters globally, resulting in detrimental impacts on freshwater aquaculture, the underlying molecular distinctions governing the response to alkaline stress between diploid and triploid crucian carp remain unknown. : This investigation explores the effects of 20 and 60 mmol NaHCO stress over 30 days on the gills of diploid and triploid crucian carp, employing histological, biochemical, and multi-omic analyses. : Findings reveal structural damage to gill lamellas in the examined tissue.
View Article and Find Full Text PDFThe efficacy and safety of L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled trials.
Front Pharmacol
January 2025
TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Background: Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease in the world. However, the current conventional approaches have not yet achieved satisfactory efficacy. As one of the most influential products in botanical medicine, L.
View Article and Find Full Text PDFFlavonoid-rich extract of Paederia scandens (Lour.) Merrill improves hyperuricemia by regulating uric acid metabolism and gut microbiota.
Food Chem
January 2025
Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China. Electronic address:
Paederia scandens (Lour.) Merrill flavonoid-rich extract (PSMF) has shown excellent xanthine oxidase (XOD) inhibitory activity in our previous study. However, the efficacy of PSMF in mitigating hyperuricemia (HUA) remains to be elucidated.
View Article and Find Full Text PDFAccounting for the role of the gastro-intestinal tract in the ammonia and urea-N dynamics of freshwater rainbow trout on long-term satiation feeding.
J Exp Biol
January 2025
Department of Zoology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
The contribution of the gut to the ingestion, production, absorption, and excretion of the extra ammonia and urea-N associated with feeding ("exogenous" fraction) has received limited prior attention. Analysis of commercial pellet food revealed appreciable concentrations of ammonia and urea-N. Long term satiation-feeding increased whole trout ammonia and urea-N excretion rates by 2.
View Article and Find Full Text PDFAnimal as the Solution II: Phenotyping for Low Milk Urea Nitrogen A1PF Dairy Cows.
Animals (Basel)
December 2024
Department of Agricultural Sciences, Faculty of Agricultural and Life Sciences, Lincoln University, Lincoln, P.O. Box 85084, Christchurch 7647, New Zealand.
The societal pressure on intensive pastoral dairying demands the search for strategies to reduce the amount of N flowing through and excreted by dairy cows. One of the strategies that is being currently explored focuses on the animal as a solution, as there are differences in N metabolism between cows even within the same herd. This work was conducted to explore such an approach in A1PF herds in New Zealand and the possibility of identifying A1PF cows that are divergent for milk urea nitrogen (MUN) concentration through phenotyping as a potential viable strategy to reduce N leaching and emissions from temperate dairy systems.
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